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38 Cards in this Set
- Front
- Back
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MIC and peak/MIC are both pharmaco_____
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dynamics
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time dependent killing is based on ___
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MIC
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concentration dependent killing depends on
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Peak/MIC
AUC/MIC |
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cidal abx are required for ___and ____
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endocarditis
meningitis because immune system is out of play |
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what is your tx goal with MIC in beta lactams
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>40% MIC
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T or F. in aminoglycosides it works best to dose less often using conc dependent peark/MIC
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true
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name the beta lactams
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penicillins
cephalosporins carbapenems monobactams |
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what are the other two major lclasses of CW abx
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glycopeptide
cyclic lipopeptide |
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what class is vanco
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glycopeptide
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DOC syphillis
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penicillin
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workhorse drug of URI and enterococcal
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aminopenicillins
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tx for lymes
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penicillin
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DOC for strep
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penicillin natural
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tx gas gangrene
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penicillin + cllinda for toxins
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T or F penicillin VK works for periodontal infectiosn and enterococcal infections
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T
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what is our precise niche staph pencillin
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semi synthetic
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T or F. semi synthetic has activity against GN and anaerobes
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false niche staph
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name a very popular drug for nosocomial and outpatient infections due to GPC
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amox/clav
pip/tazo |
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why is amox/clav good for upper and lower resp infections
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s aureus
e coli h flu moraxella klebsiella anaerobes |
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drug for SSTI cellulitis
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amox/calv
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dOC animal bites
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amox/clav
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penicillin for pseudomonas nosocomail infections
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pip/tazo
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what does the 2nd generation of ceph bring to the table
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anaerobes
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what are two biggies that ceph don't cover
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enterococci listeria
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name all your generations of ceph
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cephalexin, cefazolin, cefoxitin, ceftriaxone, cefepime, ceftaroline
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name the workhorse infections associated with ceftriaxone
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CAP
meningitis strep endocarditis URI like pyelonephritis intra abdominal infections gonorrhea |
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what third generation drug is for pseudomonas
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ceftazadime
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how do you treat gonorrhae
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ceftriaxone
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what might you use cefepime for
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serious nosocomial infections including pseudomonas
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can carbapenems treat C dif
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no
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what is aztreonam for
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GNR including pseudomonas niche role
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what is vanco for
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GP only
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DOC C diff
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vanco
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is vanco fast or slow
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slow
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what drug causes red man syndrome
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vanco
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how do you treat enterococcal that are resistant to ampicillin
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vanco
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what drug can you NOT use for pneumonia
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daptomycin
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what do you need to monitor during use of cyclic lipopeptide aka daptomycin
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myopathy CK
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