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37 Cards in this Set

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  • Back

What EN admin route is used for short term EN feeding?

nasogastric

What EN admin rough is used for long term feeding?

PEG tube


-percutaneous endoscopic gastrostomy tubes

What volume of gastric residual volume should EN feeding be discontinued or held?

250 - 500 ml

What promotility agents can be given to facilitate gastric emptying and decrease residual volume?

erythromycin or metoclopramide

How can one determine caloric requirements?

25-30 kcal/kg/day




ex: 60 kg pt




60 kg x 25 kcal/kg/day = 1500 kcal/day

How much free water should be given w/ EN feeding?

~1 ml per calorie

How much water should be mixed w/ meds if they will be given through EN tub?

flush before and after admin w/ 20 ml water




mix med w/ 10-15 ml of water

When SHOULD tpn be initiated?

pts w/ nonfunctioning or inaccessible GI tract in which duration of TPN is anticipated to be at least 7 days




or




it is anticipated that the patient will not be able to be given oral nutrition for 7 days

What are some indications for TPN?

severe pancreatitis




peritonitis




severe inflammatory bowl disease (crohns, UC)




extensive bowl resection causing malabsorption




severe N/V





What does 2-1 PN refer to?

all nutrients are mixed in the same bag and lipids are in a separate bag




Lipid should be administered over 12 hours or less; microbial growth increases after 12 hours





Why can 3-1 PN be given over 24 hours when the lipids in 2-1 must be given over less than 12 hours due to increased microbial growth after 12 hours?

when lipids are mixed w/ dextrose and AAs in 3-1 bags microbial growth is reduced due to reduced pH (more acidic) and increased osmolarity

How many kcal/g are contained in the following:




Dextrose?




Lipids?




AAs?

1 gm of 70% dextrose = 3.4 kcal/gm




1 gm of 10-20% lipid = 10 kcal/gm




1 gm of 3-20% AAs = 4 kcal/gm

How are caloric requirements calculated?

BMI < 30


-25 to 30 kcal/kg/day




BMI > 30


-11 to 14 kcal/kg/day or


-22-25 kcal/kg/day of IBW

How are fluid requirements calculated for TPN?

30-35 ml/kg/day




or




2500-3500 ml/day for pts w/out fluid restriction


-maintain urine output at 0.5-2 ml/kg/hr

What are AA requirements?

BMI < 30


i. maintenance: 0.8-1 g/kg/day


ii. moderate stress: 1.3-1.5 g/kg/day


iii. severe stress: 1.5-2 g/kg/day




BMI 30 - 40


i. 2g/kg/day based off IBW




BMI > 40


i. 2.5g/kg/day based of IBW




Ex: 60 kg pt w/ mod to severe stress


i. 60 kg x 1.5 g/kg/day = 90 g/kg/day



What percentage of TPN should be:




AA?




Lipids?




Dextrose?

AA conc. should be 2.5-4% of TPN




Lipids should be 20-30% of total cals




Dextrose should be the rest

What rate should dextrose be administered?




Why?

dextrose should be administered at a rate of 4-6 mg/kg/min to reduce risk of hepatic oxidation

How should electrolyte requirements be determined?




Na?




K?




Phosphate?




Ca?




Mg?

Na: 1-2 mEq/kg/day




K: 40-80 mEq/day (1 mEq/kg/day)




Phos: 10-40 mmol/day (or 15mmol/1000 kcal)




Ca: 10-15 mEq/day (gluconate formulation prefered)




Mg: 8-20 mEq/day (sulfate preferred)




Never too worried about Cl

What else should be provided in a TPN besides macro and micro nutrients?

trace elements:


-selenium, chromium, copper, manganese, and zinc


Parental multivitamin

When should zinc be increased?

in pts w/ high out-put fistulas, severe burns, large open wounds

When should copper and manganese be restricted in a TPN?

pts w/ severe cholestasis to prevent accumulation and toxicity



What are the safest Ca and Phos concentrations to reduce risk of precipitation?




How do AA play in to this?

Ca less than 6 mEq/L - gluconate preferred




Phos less than 30 mmol/L




AA concentration should be 2.5-4% (or higher) to prevent precipitation


-AAs form soluble complexes w/ Ca and phosphate


-AAs provide a buffer system to maintain a lower pH which helps minimize precipitation

Why should TPNs be refrigerated?

as temp increases, risk of CaPhos precipitation increases

What insulin is compatible w/ TPN?

ONLY REGULAR INSULIN

How should drugs be administered if pt is on TPN?

Through a separate IV catheter or separate lumen if given through central line




Or




hold drug and flush after administration

What antibiotic should not be given in TPN?

ceftriaxone; it precipitates w/ Ca

What other drugs should not be added to tpn?

phenytoin




meds containing proplyene glycol


-lorazepam, furosemide, digoxin




iron dextran

What bacteria primarily cause catheter related complications?

S. aureus




Candida albicans

Why should hyperglycemia be monitored and corrected if pt on TPN?

can in increase risk for nosocomial infections and wound infections

What can happen to electrolytes during refeeding syndrome?

Hypophosphatemia


Hypomagnesemia


Hypokalemia

What can happen if pt is overfed?

steatosis (fatty liver)


-watch for increased LFTs

What can conjugated bilirubin concentration indicate?

if > 2mg/dL it could indicate cholestasis and lead to cirrhosis and liver failure

Why is serum Cl monitoring necessary?

Cl and acetate salt forms can be adjusted to maintain acid-base balance

What can prealbumin values indicated?




What are important levels?

prealbumin can help one determine how nourished or malnourished a pt is




Normal range: 16-40 mg/dL


Moderate malnutrition: 11-16 mg/dL


Severe malnutrition: less than 11 mg/dL





What salt form should be given for metabolic alkalosis?

chloride

What salf form should be given for metabolic acidosis?

acetate

What can too much lipid in a TPN cause?




What medications should be accounted for?

hypertriglyceridemia




if preTPN trigs are over 400 mg/dL don't add lipids to TPN




propofol and clevidipine have lipids in the formulation