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33 Cards in this Set

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  • Back
How much of the body is composed of fluid?
60%
-2/3 of that is found within the cells and is known as Intracellular Fluid.
-1/3 of that lies outside the cells and is called Extracellular Fluid.
What are the 3 types of Extracellular Fluid and where are they found?
1.INTERSTITIAL FLUID-surrounds the cell and is outside of the blood vessels.
2.TRANSCELLULAR FLUID-includes *cerebral spinal fluid, *synovial fluid, *lymph fluid, *intraocular fluid.
3.INTRAVASCULAR FLUID-fluid containted within the blood vessels as Plasma.
Define Tonicity:
Tonicity: the ability of a solution to initiate water movement. Depends on the solutes present and their ablity to pass through a membrane. There are 3 types:
1.Isotonic
2.Hypotonic
3.Hypertonic
Tonicity: 3 types
1.ISOTONIC-fluid where normal cells will not shrink or swell. (Ex: 0.9% NaCI and LRS)
2.HYPOTONIC-fluid that causes cells to swell (water moves into the cell) (Ex: 2.5% Dextrose solution)
3.HYPERTONIC-fluid that causes cells to shrink (water moves out of the cell and into the solution) (Ex:7% NaCI)
What are Electrolytes?
Electrolytes: compounds that are formed by ions and remain as a solution. They are responsible for the alkalinity or acidity of a solution.
What are the 2 Electrolytes Routinely measured in Fluid Therapy?
1. SODIUM
2. POTASSIUM
What are the Normal Values for SODIUM and where is it most commonly found?
SODIUM normal value:
140 meq/dL
-Most abundant EXTRACELLULAR ion present!
-attracts water
-responsible for determining extracellular fluid volume
Name 4 ways other than dehydration that animals can lose sodium from their bodies:
1.Urinary loss
2.G.I. loss
3.3rd Space loss
4.Cutaneous loss
What are the Normal Values for POTASSIUM and where is it most commonly found?
POTASSIUM normal value:
3.5 to 5.0 meq/dL
-Primary INTRACELLULAR ion!
-responsible for generating electrical impulses in muscles & nerves.
-changes in plasma alter nerve and cardiac function.
What is the Maximum Rate of POTASSIUM supplementation in fluids?
Max Potassium Supplementation in fluids:
0.5 meq/kg/hr
*device called Sliding Scale of Scott determines values for potassium supplementation.
**NEVER give the undiluted form of potassium directly into an animals circulation, will cause CARDIAC ARREST! NEVER IV....Must be put into bag!
What is Acid-Base Balance?
Acid-Base Balance: refers to the regulation of hydrogen ion concentration in body fluid (pH)

**Normal pH of Arterial blood is 7.4
What is ACIDOSIS?
-Acidosis: LOW BLOOD pH that corresponds to HIGH levels of Hydrogen ion.
What is ALKALOSIS?
-Alkalosis: HIGH BLOOD pH that corresponds to LOW levels of Hydogen ion.
How do you maintain body fluid volume in an animal?
(maintenance fluid requirements)
An animals daily intake of fluid must equal the sum of Sensible and Insensible Losses.
What are SENSIBLE WATER Losses, and how much is lost?
Sensible Water Losses:
-Lost through URINE- 10mL/lb/day
-Lost through FECES-
3-5mL/lb/day
What are INSENSIBLE WATER Losses, and how much is lost?
Insensible Water Losses:
-Lost through RESPIRATIONS
-Lost through TRANSCUTANEOUS losses
Total from Both= 7.5mL/lb/day
What is the amount needed for MAINTENANCE of Normal Body Fluid per day?
Maintenance Fluids:

30 mL/lb/day
What are the Stages of DEHYDRATION?
What happens at each Stage?
Degree of Dehydration:
-less than 5%: not detectable
-6-7%: mild loss of skin elasticity
-8-9%: obvious delay in tented skin,slight prolonged CRT,dry/tacky mm's,eyes little sunk
10-12%:(Cats are at 10% if any dehydration is detected!)skin remains tented,very prolonged CRT, sunken eyes in orbits, dry mm's, possible signs of shock
-13-15%:obvious signs of shock, Death Imminent :(
What is the amount needed for REPLACEMENT fluids?
*Remember, 1L=1kg, so for every kg of body weight the animal has lost it has also lost 1L of fluid.
Replacement Fluids:

% of dehydration X body weight(kg) X 1000

(% x kg x 1000)

*daily fluid requirements: replacement volume + maintenance volume
Define Dehydration:
Dehydration: reduced total body water w/ preservation of vascular volume.
(replace slowly as not to over expand the vascular space)
Define Hypovolemia and Shock:
Hypovolemia/Shock: reduced intravascular volume (which can impair cardiac output).
(must rapidly replace fluids in order to re-expand the intravascular volume.
What are the Signs of Hypovolemia and Shock?
Signs of Hypovolemia/Shock:
-weakness
-CRT longer than 3 seconds
-pale mm's
-low body temp.
What are the Hypovolemia/Shock dose of fluids?
Hypovolemia/Shock fluid dose:
*these considerations should always be considered in any Trauma Patient!
-Require fluid replacement at:

60 mL/kg/hr (emergency fluid)
What is a COLLOID?
Colloid: fluid product that contains large molecular weight molecules that remain in the vascular space until they are degraded by the body.
-they are used to increase oncotic pressure
-Can be used in Shock Situations!
What is the Most Commonly used COLLOID?
HETASTARCH most common used product
What rate is COLLOID administered at?
-The Flow Rate is up to 20mL/kg/day IV over whole day, or can be given over 30 min. for DOGS.
CATS flow rate: 15mL/kg slowly for 20-30 minutes.
What is the Electronic Infusion Pump Rate Method?
Electronic Infusion Pump Method: involves the use of an electronic infusion pump, a bag of fluids, and an IV drip set.
(calculated by machine @ ml/hr)
Common Solutions
Lactated Ringer Solution LRS
Characteristics:
LRS: this is used for most maintenance situations
-lactate helps prevent and treat metabolic acidosis.
-provides normal level of potassium to prevent hypokalemia from vomiting, lack of daily intake, etc
Common Solutions
Normal Saline (0.9% NaCI)
Characteristics:
Normal Saline (o.9% NaCI):
-an isotonic fluid
-most commonly used in animals who need a normal osmotic solution w/o potassium, like hyperkalemic
Common Solutions
LRS with 5% Dextrose or 0.45% NaCI with 5% Dextrose
Characteristics:
LRS w/ 5% Dextrose or 0.45% NaCI w/ 5% Dextrose:
-used in animals that need a sourse of Dextrose to maintain blood sugar levels, like hypoglycemic
Common Solutions
Fluid Supplements-Dextrose 50%
Characteristics:
Fluid Supplements-Dextrose 50%:
-used to add Dextrose to any fluid (up to 5%)
-Potassium Chloride: very common additive (use Sliding Scale of Scott to determine amount to add)
What are Constant Rate of Infusions?
Constant Rate of Infusions: drugs that are administered as an infusion (usually placed in a bag of fluids) and are given continuously over a set period of time. (pain meds, electrolytes, anti-sezure meds, and antibiotics are commonly given as constant infusion)
In order to determine how much of a drug needs to be added to a bag of fluids, what 5 key pieces of information do we need to know?
5 key pieces of info to know how much drug to add to a bag of fluid:
1.rate at which fluids are being administered
2.drug name and dose
3.drug concentration
4.patient weight
5.size of fluid bag being used