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26 Cards in this Set

  • Front
  • Back
Intracellular fluid
42% of total body weight
Extracellular fluid
17% of total body weight
Hypertonic solution
A solution of higher osmotic pressure, 3% sodium chloride, pulls fluid from cells, causing them to shrink.
Hypotonic solution
A solution of lower osmotoc pressure, 0.45 sodium chloride, moves fluid into the cells, causing them to enlarge.
Isotonic solution
A solution with the same osmolarity as blood plasma - normal saline, 0.9% sodium chloride, expand the body's fluid volume without causing a fluid shift.
Osmosis
k
Osmotic pressure
k
Diffusion
mj
Filtration
j
Active transport
l
Fluid intake
c
Hormonal regulation
cc
Fluid output regulation
cc
Regulation of electrolytes
Cationes
c
Sodium Regulation
135 - 145 mEq/L
Most abundant cation - 90%. Major contributers to maintaining water balance. Sodium intake is regulated by dietary intake and aldosterone secretion.
HYPONATREMIA - lower-than-normal concentration of sodium in the blood (serum), which can occur with a net sodium or net water loss. Occurs frequently in seiously ill patients.
vomiting, diarrhea, kidney disease resulting in salt wasting, diuretics, adrenal insufficiency, excessive persirations, burns, polydipsia. Signs and symptoms - personality change, postural hypotension, postural dizziness, abdominal cramping, nausea and vomiting, diarrhea, tachycardia, dry mucous membranes, convulsions, coma.
HYPERNATREMIA - greater-than-normal concentrations of sodium.
Excess salt intake, Axcess aldosterone secretion, diabetes insipidus, increased senible and insensible water loss, water deprivation. Signs&symptoms - extreme thirst, dry and flushed skin, dry and sticky tongue and mucous membranes, postural hypotension, fever, agitation, convulsions, restlessness, irritability
Potassium regulation
3.5 - 5 mEq/L
Major electrolyte in the intracellular compartment.
Regulates may metabolic activities and is necessary for glycogen deposits in the liver and skeletal muscle, transmission and conduction of nerve impulses, normal cardiac conduction and skeletal and smooth muscle contraction.
Dietary intake and renal excretion regulate K.
The body conserves K poorly, so any condition that increases urine output decreases the serum K concentration.
HYPOKALEEMIA - use of potassium-wasting diuretics, diarrhea, vomiting, alkalosis, excess aldosterone secretion, polyuria, sxtreme sweating, excessive use of potassium-free IV solutions, Signs&symptoms - weakness and fatigues, muscle weakness, nausea and vomiting, intestinal distention, decreased bowel sounds, decreased deep tendon reflexes, ventricular dysrhythmias, paresthesias and weak, irregular pulse.
HYPERKALEMIA - renal failure, fluid volume deficit, massive cellular damage such as from burns and trauma. Adrenal insufficiency, acidosis, rapid infusion of stored blood, use of potassium-sparing diuretics. Signs&symptoms - anxiety, dysrhythmias, paresthesia, weakness, abdominal cramps, diarrhea. ECG abnormalties: peaked T wave and widened QRS complex (bradycardia, heart block, dysrhythmias); eventually QRS pattern widens and cardiac arrest occurs.
Calcium regulation
Stored in bone, plasma and body cells.
Calcium is necessary for bone and teeth formation, blood clotting, transmission of nerve impulses and muscle contraction.
HYPOCALCEMIA - rapid administration of blood transfusions containing citrate, hypoalbuminemia, hypoparathyroidism, vitamin D deficiency, pancreatitis, alkalosis, chronic renal failure, chronic alcoholism. Signs&symptoms - numbness and tingling of fingers and circumoral (around the mouth) region, hyperactive reflexes, muscle cramps, contraction of facial muscles when facial nerve is tapped.
HYPERCALCEMIA - hyperparathyroidism, osteoporosis, prolonged immobilization, acidosis. Signs&symptoms - anorexia, nausea and vomiting, weakness, hypoactive reflexes, lethargy, flank pain (from kidney stones), decreased level of consciousness, personality changes, cardiac arrest.Elevated blood urea nitrogen (BUN) level 25 mg/100 mL and elevated creatinine level 1.5 mg/100 mL caused by fluid volume deficit or renal damage caused by urolithiasis; ECH abnormalties: heart block.
Magnesium regulation
1.5 to 2.5 mEq/L
Essential for enzyme activities, neurochemical activities, and cardiac and skeletal muscle excitability.
Regulated by dietary intake, renal mechanisms, and actions of the parathyroid hormone. About 50-60% is contained within the bone.
HYPOMAGNESEMIA - malnutrition and alcoholism, diarrhea, vomiting, nasogastric drainage, fistulas, diseases of small intestine, excessive loss resulting from thiazide diuretics, aldosterone excess, polyuria. Signs&symptoms - muscular tremors, hyperactive deep tendon reflex, confusion and disorientation, tachycardia, hypertension, dysrhythmias.
HYPERMAGNESEMIA - renal failure, excess oral or parenteral intake of magnesium. Signs&symptoms - acute elevations in magnesium levels:hypoactive deep tendon reflexes, decreased depth and rate of respirations, hypotension, flushing. Prolonged QT intercal, AV block.
Regulation of electrolytes
Aniones
f
Chloride regulation
95-105 mEq/L
Major anion in ECF. The transport of chloride follows sodium. Regulated by dietary intake and the kidneys.
Bicarbonate regulation
d
Phosphorus-Phosphate regulation
d
Regulation of Acid-Base Balance
d
Chemical regulation
d
Biological regulation
d
Physiological regulation
d