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22 Cards in this Set

  • Front
  • Back
Fluid Compartments
Compartments seperated by barriers:

Plasma membrane seperates ICF (Intercellular) and ECF (Extracellular)

Blood vessel walls separate ECF into compartments

2/3 Intercellular
1/3 Extracellular
Extracellular Fluids
80% Interstitial (between cells, lymph, CSF, synovial, eyes, ears

20% plasma
Movement Between Compartments
Governed by osmotic and hydrostatic pressures
Influence on osmotic pressure
Electrolytes have more influence than nonelectrolytes

Dissolves ions like sodium anything with a possitive or negative charges
Filtrate
Capillary hydrostatic pressure pushes filtrate out of capillaries;

capillary osmotic pressure draws fluid into capillaries
Solute movement depends on
Size, charge, and if a transport protein is needed

This is why electrolytes have more influence on osmotic pressure
Water moves freely between
ICF and ECF
Water gain and loss must
balance
Sources of water gain
Ingested Liquids
Ingested Foods
Metabolic Activity
Sources of Water loss
Kidneys - urine
Skin - sweat
Lungs - exhaled
Regulation of water gain
Thirst center of hypothalamus governs urge to drink

4 factors that stimulate
-Osmoreceptors
-Angiotensin II levels in blood
-Dry mouth
-Baroreceptors in heart and blood vessels
Regulation of Water and Solute loss
4 Hormones regulate this

Angiotensin II and Aldosterone
Increases reabsorption of Na+ and Cl-

ANP increases excretion of Na+ and Cl- (increases water loss)

ADH Decreases water loss

Body fluid volume determined mainly by urinary loss of NaCl

Body fluid osmolality determined mainly by urinary water loss
Functions of Electrolytes
Control osmosis of water between fluid compartments

Maintain acid-base balance

Carry electrical current

Act as cofactores for enzyme activity
Intercellular fluid
Protein anions - about 3X more soluble proteins than in plasma

Potassium

Hydrogen phosphate HPO4 2-

Magnesium
Extracellular Fluid
Proteins - more in plasma than in interstitial fluid

Sodium

Chloride

Bicarbinate
Sodium
Fluid-Electrolyte balance, generation and conduction of APs (Action potentials)
Chloride
Balances anions and is part of gastric juice
Potassium
Establishes resting membrane potential and repolarization, pH of body fluids in exchange for H+
Bicarbonate
ECF anion important in acid-base balance
Calcium
Most abundant mineral; bones, teeth, clotting, neurotransmitters release, muscle tone
Phosphate
buffer of excess H+, attaches to ADP to form ATP
Magnesium
Intracellular cation, enzyme cofactor, neuromuscular activity, synaptic transmission, cardiac function