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62 Cards in this Set
- Front
- Back
capillary fluid flow is directly related to the difference in pressure between the arterial and venous end of capillaries
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colloid osmotic pressure
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(caused by the pumping action of the heart) pushes water, electrolytes, and nutrients through the capillary walls
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arterial hydrostatic pressure
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(created by plasma proteins) pulls water, electrolytes, and cell waste products into the capillary through the capillary walls
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venous colloid osmotic pressure
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the movement of molecules from an area of higher concentration to an area of lower concentration
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dffusion
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the balance affected by the movement, replacement, and transformation, retention, and/or excretion of various materials essential to life
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fluid and electrolyte
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are inside the cells
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intracellular fluids (ICF)
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are outside the cells
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extracellular fluids (ECF)
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inside the blod vessels
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intravascular fluids
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lie between the blood vessels and the cells aka a "third space"
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interstitial fluids
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What % of fluids are in the intracellular component in most adults
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60 %
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ICF make up ___ % of body weight
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40 %
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ECF make up ___ % of body weight
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20 %
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functional unit of the kidney
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nephron
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The nephron filters blood plasma to remove: (3)
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-the end products of metabolism,
-drugs -any excess water or solutes, reabsorbs water and solutes as needed, maintains fluid, electrolyte, and acid-base balance |
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Nephron consists of
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Glomerulus, Bowman's capsule, proximal tubule, descending limb of the Loop of Henle, ascending limb of the Loop of Henle, distal tubule, collecting tubule, and surrounding peritubular capillaries
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As filtrate rounds the Loop of Henle and moves into the ascending limb; water is retained as ____ and ____ is pumped out.
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chloride and sodium
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____ and ____ acts to influence water and electrolyte balance in the distal tuble
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ADH, aldosterone
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important in the regulation of fluid balance
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the amount of blood and pressure of the blood entering the kidneys
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blood arrives at the kiney via the _____ ______.
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renal artery
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When blood arrives to the renal artery it flows in to _____ which leads to and from the ____.
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arterioles, glomerulus
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Plasma in the glomerulus is filtered through
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semi-permeable membrane
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After plasma is filtered in the glomerulus it goes into the
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Bowman's capsule
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Where does filtrate go after leaving the Bowman's capsule?
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renal tubule system
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Once filtrate enters the renal tubule system it flows into the
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proximal tubule
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Filtrates leaves the proximal tubule and descends and ascends in the
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Loop of Henle
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When filtrate flows through the Loop of Henle it flows through
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the distal tubule and into the collecting duct
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What causes filtrate to become hypertonic in the descending loop?
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water flows out and sodium flows in
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What cause changes in the rate at which blood is filtered by the glomerulus and, ultimately, the rate and amount of urine formation?
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changes in blood volume as blood pressure
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Highly permeable to water, but not urea and sodium
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descending Loop of Henle
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Highly permeable to chloride and sodium, but not water
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ascending Loop of Henle
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osmotic concentration per Liter of solution
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Osmolarity
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osmotic concentration per Kg of solvent
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Osmolality
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dominant particle in ICF
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potassium
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dominant partivle in ECF
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sodium
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What 3 factors govern osmolarity
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1. Electrolytes, especially sodium
2. Glucose and urea 3. Plasma proteins (albumin) |
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forces fluid out of the capillaries
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hydrostatic pressure
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pulls fluid back in capillaries
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colloid osmotic pressure
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can cross capillary membranes, but can not cross cell membranes
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sodium
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Occurs when sodium stays in the cell and the cell swells
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hypoxia
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are the main negatively charged intravascular fluid anions, balance the positive charge of sodium in osmolarity
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plasma proteins (albumins)
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plasma proteins (albumins) create a {colloid osmotic/hydrostatic} pressure
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colloid osmotic pressure
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made in hypothalamus, stored in posterior pituitary gland
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ADH
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stimulates the pituitary to increase or decrease the release of ADH
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hypothalamus
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produced by adrenal cortex
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aldosterone
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acts on renal distal convoluted tubule
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aldosterone
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acts on renal collecting tubules to regulate reabsorption or elimination of water
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ADH
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made in adrenal gland
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Glucocorticoids (hydrocortisone and cortisol)
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promote resorption of sodium, water by the kidney, and affect total blood volume
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Glucocorticoids (hydrocortisone and cortisol
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Glucocorticoids can cause an increase in
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total blood volume
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naturally occurring fatty acids which function in a variety of processes including maintenance of renal blood flow
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Prostaglandins
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factors that reduce renal blood flow and cause prostaglandin release are (3)
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1. Vasoconstriction of the renal vessels (capillaries)
2. Decrease in total blood volume 3. Decrease in blood flow to the kidney because of heart failure |
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(+) Cations
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Na, K, Ca, Mg
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(-) Anions
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Cl, bicarbonate, phosphate, sulfate, protein
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ECF has large amounts of
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Na, Cl, and bicarbonate
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ICF has (small/large) amounts of: K, phosphate, sulfate, and protein
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large
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EFC has (small,large) amounts of K, phosphorous, sulfate, and protein
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small
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IFC has small amounts of
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Na, Cl, and bicarbonate
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competes with H for elimination in the kidney tubules
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Potassium
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What promotes K loss in urine?
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increase in K levels stimulates aldosterone release from the adrenal gland
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Functions in: muscle contractile ability, correct neural function, strength of bone and teeth, blood clotting
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calcium
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Functions in neuromuscular irritability, conduction of nerve impulses and muscle contraction, osmotic pressure of ECF, acid-base balance, water balance, and gland secretion
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Sodium
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functions in neuromuscular irritability, the ability of nerve and muscle cell to fire, cardiac impulse conduction and muscle cell contractility, ICF osmolarity, regulation of acid-base balance, activation of enzyme reactions, influencing kidney function
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Potassium
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