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5 Cards in this Set

  • Front
  • Back
flucytosine
flurorinated pyrimidine
mechanism of action
penetrates fungal cells

converted to fluorouracil
(metabolic antagonist)
spectrum of activity
cryptococcus and candida
therapeutic use
with amphotericin B - severe systemic infections (septicemia, endocarditis, pulmonary and uti, meningitis
significant interaxns
synergy with amphotericin b and fluconazole