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5 Cards in this Set
- Front
- Back
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flucytosine
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flurorinated pyrimidine
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mechanism of action
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penetrates fungal cells
converted to fluorouracil (metabolic antagonist) |
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spectrum of activity
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cryptococcus and candida
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therapeutic use
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with amphotericin B - severe systemic infections (septicemia, endocarditis, pulmonary and uti, meningitis
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significant interaxns
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synergy with amphotericin b and fluconazole
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