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5 Cards in this Set

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Fluoroquinolones

1st Generation: 1 prototype

2nd Generation: 2 prototype
1st Generation:
*Ciprofloxin (CIPRO)

2nd Generation:
*Levofloxin (LEVOQUIN)
*Maxifloxacin (Avelox)
Fluoroquinnolones;
1st Generation

*Used Primarily for Gram _1_
*Good _2_ coverage, no _3_
coverage
*Infectious disease
-salmonella, shigella
-travelers diarrhea
*STD
-Prostatitis
-urethritis: C & G
1. negative
2. Staph
3. Strep
4. Chlamydia
5. Gonnorrhea
Fluoroquinolones
2nd Generation

*All as in 1st generation
*CAP including __1__ pn
*S__2__ & B__3__
*__4__ pneumoniae
*ANTHRAX!!!!!
1. Strep
2. Sinitis
3. Bronchitis
4. Atypical
Fluoroquinolones

*Well absorbed __1__
-same dose IV as PO
*__2___ metabolism with __3__ exretion
-good for __4__
*Good penetration in all _5__
-higher conc. levels in
_5_ than __6__
1. Orally
2. Hepatic
3. Renal
4. UTI
5. tissue
6. serum
Fluoroquinolones Side Effects

-CNS: sleep distrubace,
agitation, seizures

-Bone & Tendons: cartilage
_1__ and tendon __2_
*contraindicated below _3
*caution in __4__

Inhibit metabolism of _5__ &
__6_
1.erosion
2. weakness
3. 18
4. athletes
5. caffeine
6. theocphyllin