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36 Cards in this Set

  • Front
  • Back
echothiophate
poisons, biowarfare, nerve gas. seizures, paralysis, death.
tacrine
slows Alzheimer's progression.
endrophonium
used in the diagnosis of myasthenia gravis. short acting.
neostigmine
reverse anesthesia paralysis. stimulate the bladder. does not cross BBB.
physostigmine
treat atropine poisoning. last resort open angle glaucoma. crosses BBB.
bethanecol
treats post-op bladder paralysis. M2 M3 agonist. Does not cross BBB so no M1.
ipratropium, tiotropium
treat COPD and asthma. does not inhibit ciliary movement. alternative to beta agonist. M3 antagonist.
pirenzipine
ulcers. M1 antag.
atropine
antidote for AchE inhibitor (echothiophate, organophosphates).
scopolamine
crosses BBB, M1 selective. motion sickness and anesthensia adjunct (amnesia, drowsiness)
pilocarpine
closed/open glaucoma. applied topically to eye (M3). M1 M2 M3 though.
succinylcholine
used for endotrachial intubation in emergency. fast onset, fast offset. only depolarizing NMJ blocker. cannot reverse with AchE.
tubocurarine
used for endotrachial intubation in surgery. longer acting. can reverse with AchE. isoquinolone nucleus = histamine release.
mivacurium
endotrachial intubation. fast onset, fast offset. isoquinolone nucleus = histamine release.
botulinum
botox. synaptobren & snap25 degrade. paralysis
varenicline
smoking cessation. does not cause dopamine peak.
reserpine
used as a HT drug in past. potent and used for severe / refractory HT.
guanethidine
used as a HT drug in past. potent and used for severe / refractory HT.
clonidine
HT with renal dz. reduces left hypertrophy and cholesterol.
A-methyl-DOPA
HT with renal dz. reduces left hypertrophy and cholesterol.
Hydralazine
used in severe HT in combo to reduce severe SE (lupus, edema). artery only (afterload)
minoxidil
used in severe HT in combo to reduce severe SE (hirsutism, edema). artery only (afterload)
sodium nitroprusside
acute management of hypertensive crisis. IV only (cyanide). veins and arteries (preload and afterload).
chlorthalidone
mild HT alone or severe in combo. inexpensive. 15mmHg ceiling. hypokalemia, hyperglycemia, hyperuricemia, increased cholest & tri.
hydrochlorothiazide
mild HT alone or severe in combo. inexpensive. 15mmHg ceiling. hypokalemia, hyperglycemia, hyperuricemia, increased cholest & tri.
amiloride
not effective HT alone, use with other diuretic. SE (gynecomastia).
propranolol
mild HT alone or severe in combo. effects slow over time. increase tri, decrease HDL.
acebutolol
partial B1 antag. mild HT with bradycardia. increase tri, decrease HDL.
prazosin
severe HT and benign prostatic. decrease cholesterol. arrythmias.
captopril
mild HT. increase bradykinin PGI & NO. cough, ageusia, birth defects, hyperkalemia if with K sparing diuretic.
losartan
(ARB) mild HT. no cough.
nifedipine
mild HT. effects vascular smooth muscle more. reflex tachy. associated with arryth (use BB, diuretics, ACE first)
diltiazem
mild HT. effects cardiac muscle more. cardiac depression.
sildenafil
pulmonary arterial HT. cheaper than bosentan.
fosinepril
ace inhibitor, broken down by liver
pralidoxime (pam2)
reverse echothiophate poisoning