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36 Cards in this Set
- Front
- Back
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echothiophate
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poisons, biowarfare, nerve gas. seizures, paralysis, death.
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tacrine
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slows Alzheimer's progression.
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endrophonium
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used in the diagnosis of myasthenia gravis. short acting.
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neostigmine
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reverse anesthesia paralysis. stimulate the bladder. does not cross BBB.
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physostigmine
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treat atropine poisoning. last resort open angle glaucoma. crosses BBB.
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bethanecol
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treats post-op bladder paralysis. M2 M3 agonist. Does not cross BBB so no M1.
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ipratropium, tiotropium
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treat COPD and asthma. does not inhibit ciliary movement. alternative to beta agonist. M3 antagonist.
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pirenzipine
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ulcers. M1 antag.
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atropine
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antidote for AchE inhibitor (echothiophate, organophosphates).
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scopolamine
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crosses BBB, M1 selective. motion sickness and anesthensia adjunct (amnesia, drowsiness)
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pilocarpine
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closed/open glaucoma. applied topically to eye (M3). M1 M2 M3 though.
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succinylcholine
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used for endotrachial intubation in emergency. fast onset, fast offset. only depolarizing NMJ blocker. cannot reverse with AchE.
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tubocurarine
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used for endotrachial intubation in surgery. longer acting. can reverse with AchE. isoquinolone nucleus = histamine release.
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mivacurium
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endotrachial intubation. fast onset, fast offset. isoquinolone nucleus = histamine release.
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botulinum
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botox. synaptobren & snap25 degrade. paralysis
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varenicline
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smoking cessation. does not cause dopamine peak.
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reserpine
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used as a HT drug in past. potent and used for severe / refractory HT.
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guanethidine
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used as a HT drug in past. potent and used for severe / refractory HT.
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clonidine
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HT with renal dz. reduces left hypertrophy and cholesterol.
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A-methyl-DOPA
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HT with renal dz. reduces left hypertrophy and cholesterol.
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Hydralazine
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used in severe HT in combo to reduce severe SE (lupus, edema). artery only (afterload)
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minoxidil
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used in severe HT in combo to reduce severe SE (hirsutism, edema). artery only (afterload)
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sodium nitroprusside
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acute management of hypertensive crisis. IV only (cyanide). veins and arteries (preload and afterload).
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chlorthalidone
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mild HT alone or severe in combo. inexpensive. 15mmHg ceiling. hypokalemia, hyperglycemia, hyperuricemia, increased cholest & tri.
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hydrochlorothiazide
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mild HT alone or severe in combo. inexpensive. 15mmHg ceiling. hypokalemia, hyperglycemia, hyperuricemia, increased cholest & tri.
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amiloride
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not effective HT alone, use with other diuretic. SE (gynecomastia).
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propranolol
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mild HT alone or severe in combo. effects slow over time. increase tri, decrease HDL.
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acebutolol
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partial B1 antag. mild HT with bradycardia. increase tri, decrease HDL.
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prazosin
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severe HT and benign prostatic. decrease cholesterol. arrythmias.
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captopril
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mild HT. increase bradykinin PGI & NO. cough, ageusia, birth defects, hyperkalemia if with K sparing diuretic.
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losartan
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(ARB) mild HT. no cough.
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nifedipine
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mild HT. effects vascular smooth muscle more. reflex tachy. associated with arryth (use BB, diuretics, ACE first)
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diltiazem
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mild HT. effects cardiac muscle more. cardiac depression.
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sildenafil
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pulmonary arterial HT. cheaper than bosentan.
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fosinepril
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ace inhibitor, broken down by liver
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pralidoxime (pam2)
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reverse echothiophate poisoning
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