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1 Cards in this Set
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Aspirin (ASA)
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moa - Acetylates and irreversibly inhibits cyclooxygenases (both COX-1 and COX-2) to prevent conversion of arachidonic acid to thromboxaneA2. Increases bleeding time. No effect on PT, PTT.
Clinical use: Antipyretic, analgesic, anti-inflammatory, antiplatelet drug Toxicity: Gastric ulceration, bleeding, hyperventilation, Reye's syndrome, tinnitus (CN VIII) |
