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6 Cards in this Set
- Front
- Back
Hydroxyurea
|
inhibits ribonucleotide reductase
|
|
6- Mercaptopurine (6-MP)
|
blocks de novo purine synthesis
|
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5- Flourouracil (5-FU)
|
inhibits thymidylate synthase
(v dTMP) |
|
Methotrexate (MTX)
|
inhibits dihydrofolate reductase
(v dTMP) |
|
Trimethoprim
|
inhibits BACTERIAL dihydrofolate reductase
(v dTMP) |
|
Fluoroquinolones
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inhibit DNA gyrase (specific prokaryotic topoisomerase)
|