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35 Cards in this Set

  • Front
  • Back
This gene is related to what tumor/cancer? gene product?
abl
CML- tyrosine kinase
This gene is related to what tumor/cancer? gene product?
c-myc
Burkitt’s lymphoma- transcription factor
This gene is related to what tumor/cancer? gene product?
bcl-2 chromosome mutation?
Follicular and undifferentiated lymphomas (inhibits apoptosis)- anti- apoptotic molecule, blocks release of cyt. C

14:18
This gene is related to what tumor/cancer? gene product?
erb-B2
Breast, ovarian, and gastric carcinomas- tyrosine kinase
This gene is related to what tumor/cancer? gene product?
ras
Colon carcinoma- GTPase
This gene is related to what tumor/cancer? gene product?
L-myc
Lung tumor- transcription factor
This gene is related to what tumor/cancer? gene product?
N-myc
Neuroblastoma- transcription factor... you would see homer-wright pseudo rosettes
This gene is related to what tumor/cancer? gene product?
ret
Multiple endocrine neoplasia (MEN) types IIA and IIB- tyrosine kinase
This gene is related to what tumor/cancer? gene product?
c-kit
Gastrointestinal stromal tumor (GIST)- cytokine receptor
This gene is related to what tumor/cancer? gene product?
PDGF-B
astrocytoma
Name the neoplasm associated with the condition...
2. Xeroderma pigmentosum, albinism
2. Melanoma, basal cell carcinoma, and especially squamous cell carcinomas of skin
Name the neoplasm associated with the condition...
Chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants
3. Gastric adenocarcinoma
Name the neoplasm associated with the condition...
Tuberous sclerosis (facial angiofibroma, seizures, mental retardation)
Astrocytoma, angiomyo lipoma, and cardiac rhabdomyoma
Name the neoplasm associated with the condition...
Actinic keratosis
Squamous cell carcinoma of skin
Name the neoplasm associated with the condition...
Barrett’s esophagus (chronic GI reflux)
Esophageal
adenocarcinoma
Name the neoplasm associated with the condition...
Immunodeficiency states
Malignant lymphomas
Name the neoplasm associated with the condition...
Plummer-Vinson syndrome (atrophic glossitis, esophageal webs, anemia; all due to irondeficiency)
Squamous cell carcinoma of esophagus
Name the neoplasm associated with the condition...
Cirrhosis (alcoholic, hepatitis B or C)
Hepatocellular carcinoma
Name the neoplasm associated with the condition...
Ulcerative colitis
Colonic adenocarcinoma
Name the neoplasm associated with the condition...
Paget’s disease of bone
2° osteosarcoma and fibrosarcoma
For the condition name the neoplasm associated with it...
Radiation exposure
Sarcoma, papillary thyroid
cancer
For the condition name the neoplasm associated with it...
AIDS
Aggressive malignant lymphomas (non-Hodgkin’s) and Kaposi’s sarcoma
For the condition name the neoplasm associated with it...
Autoimmune diseases (e.g., Hashimoto’s thyroiditis, myasthenia gravis)
Lymphoma
For the condition name the neoplasm associated with it...
Acanthosis nigricans (hyperpigmentation and epidermal thickening)
Visceral malignancy- (stomach, lung, breast, uterus)
For the condition name the neoplasm associated with it...
Dysplastic nevus
Malignant melanoma
For the following virus name the associated cancer...
HTLV-1
Adult T-cell leukemia/ lymphoma
For the following virus name the associated cancer...
HBV, HCV
Hepatocellular CA
For the following virus name the associated cancer...
EBV
Burkitt's lymphoma, Hodgkin's lymphoma, nasopharyngeal CA
For the following virus name the associated cancer...
HPV (16,18)
Cervical CA, penile and anal
For the following virus name the associated cancer...
HHV-8
Kaposi's sarcoma, body cavity fluid B-cell lymphoma
For the following virus name the associated cancer...
HIV
Primary CNS lymphoma
For the following virus/microbe name the associated cancer...
H.pylori
Gastric adenocarcinoma and lymphoma
For the following virus/microbe name the associated cancer...
schistosoma haematobium
SCC of transitional epithelium of bladder
For the following virus/microbe name the associated cancer...
Clonorchis sinensis
Biliary CA
For the following virus/microbe name the associated cancer...
Strep. Bovis
colon CA