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27 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
atropine-like side effects
tricyclics
cardiac toxicity
doxorubicin, daunorubicin
coronary vasospasm
cocaine
None
cutaneous flushing
niacin (lipid lowerer, increases HDL), CCB, adenosine, vancomycin (red man syndrome!)
torsades de pointes
class III antiarrythm (sotalol), class IA antiarrhythm. (quinidine), cisapride
agranulocytosis (3)
clozapine (atypical antipsych, least EPS); carbamazepine (AED, mood stabilizer, P450 inducer); colchicine
aplastic anemia
chloramphenicol, benzene, NSAIDs; also: propylthioracil, methimazole (inhibit organificatin and coupling of thyroid hormone synth)
None
gray baby syndrome
(ab distention, progressive pallid cyanosis, vasomotor collapse) chloramphenicol (binds 50s, inhibits peptidlytransferase)
hemolysis in G6PD deficient pts
sulfonamides, INH, aspirin, ibuprofen, primaquine, nitrofurantoin (abx)
thrombotic complications
OCPs
cough
ace inhibitors (bradykinin!)
pulmonary fibrosis
bleomycin (induces free radical formation, for testicular cacner, lymphomas--ABVD regimen); amiodarone (class IA antiarrhthm); busulfan (alkylates DNA, CML, also causes hyperpigmentation)
acute cholestatic hepatitis
macrolides (dont give to preggers!)
focal to massive hepatic necrosis
halothane (inhaled anesthetic); valproic acid; acetaminophen; Amanita phalloides (mushroom poison alpha amanitin-->inhibits euk RNA pol)
gynecomastia
Some Drugs Create AwesomE Knockers--Spironolactone, Digitalis, Cimetidine, Alcohol chronique, Estrogens, Ketoconazole
gingival hyperplasia
phenytoin
osteoporosis
corticosteroids, heparin
photosensitivity
sulfonamides, amiodarone, tetracycline; also 5-FU
None
SLE-like syndrome
hydralazine (antiHTN for preggers, stim cGMP); INH; procainamide (Class IA antiarrh.); phenytoin
Fanconi's syndrome
expired tetracycline
interstitial nephritis
methicillin; also acute interstitial nephritis: NSAIDs, beta lactams, sulfa diuretics, phenytoin, cimetidine, methyldopa
None
hemorrhagic cystitis
cyclophosphamide, ifosfamide
diabetes insipidus
lithium, demeclocycline
seizures
bupropion (heterocyclic antidepressant, no sexual side effects); imipenem/cilastin
disulfiram-like reaction
metronidazole, some cephalosporins, procarbazine (antineoplastic alkylator); sulfonylureas
nephrotoxicity/neurotoxicity
polymyxins
nephrotoxicity/ototoxicty
aminoglycosides, loop diuretics, cisplatin