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20 Cards in this Set
- Front
- Back
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inactivates elongation factor
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corynebacterium diphtheriae
pseudomonas aeruginosoa |
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exotoxin A
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pseudomonas aueruginosa- inactivate EF-2
strept pyogenes- toxic shock syndrome |
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causes pharyngitis and psuedomembrane in throat
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diphtheria toxin
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inactivate 60S ribosome by cleaving rRNA
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shigella and EHEC
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shiga-like toxin
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EHEC
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overactivates adenylate cyclase (increased cAMP) without going through Gs
increases Cl secretion |
heat-labile toxin of ETEC
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heat labile toxin
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ETEC
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overactivates gyanylate cyclase to increase cGMP and decrease reabsorption of NaCl and H2O in the gut
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ETEC and yersinia (heat stable toxin)
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ETEC
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heat labile toxin
heat stable toxin |
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yersinia enterocolitica
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heat stable toxin
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edema factor
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bacillus anthracis
mimics adenylate cyclase to increase cAMP |
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cholera toxin
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overactivates adenylate cyclase (increased cAMP) by permanently activating Gs
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pertussis toxin
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overactivates adenylate cyclase disabling Gi and impairing phagocytosis
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tetanospasmin
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inhibits GABA release in the spinal cord
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botulinum oxin
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inhibits release of ACh at the NMJ
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alpha toxin
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clostridium perfringens
phospholipase that degrades tissue, cell membranes |
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streptolysin O
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protein that degrades membranes
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exotoxin A (causing TSS)
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bring MHC II and TCR in proximity to cause overwhelming release of IFN-y and IL-2 ,causing shock
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TSST-1
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bring MHC II and TCR in proximity to cause overwhelming release of IFN-y and IL-2 ,causing shock
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exotoxin A from:
TSST-1 from: |
exotoxin A- s. pyogenes
TSST-1: s. aureus |
