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20 Cards in this Set
- Front
- Back
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fat soluble vitamins?
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ADEK
toxicity more common (than water souble) b/c accumulate in fat |
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common cause of fat soluble vitamin deficiencies?
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malabsorption syndromes (steatorrhea)
-cystic fibrosis -sprue or mineral oil intake |
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which water soluble vitamins do not wash out of the body easily?
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B12 and folate, which are stored in the liver
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common cause of dermatitis, glossitis, and diarrhea?
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B-complex deficiencies
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vitamin A is used to treat?
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measles
AML, subtype M3 |
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vitamin A's name? found?
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retinol
found in liver & leafy vegetables |
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vitamin A function?
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retinol
antioxidant constituent of visual pigments essential for normal differentiation of epithelial cells into specialized tissue (pancreatic cells, mucus-secreting cells) prevents squamous metaplasia |
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vitamin deficiency - night blindness, dry skin?
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Vitamin A
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vitamin excess - arthralgias, fatigue, headaches, skin changes, sore throat, alopecia?
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Vitamin A
(also is teratogenic) |
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vitamin that is teratogenic? causes?
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vitamin A
cleft palate, cardiac abnormalities |
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before prescribing isotretoin for acne what must be done?
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pregnancy test
Vitamin A is teratogenic |
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Vitamin B1 name? MOA?
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Thiamine pyrophosphate (TPP)
cofactor for DECARBOXYLATION rections -Pyruvate dehydrogenase (TCA) -alpha ketoglutarate dehydrogenase (TCA cycle) -Transketolase (HMP shunt) -Branched chain AA dehydrogenase |
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what enzyme is involved in decarboxylation reactions?
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Thamine, B1
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vitamin deficiency - impaired glucose breakdown, ATP depletion (worsened by glucose infusion)?
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Thiamine, B1 deficiency
seen in alcoholism & malnutrition highly aerobic tissues effected first (brain & heart) Wernicke-Korsakoff; berberi |
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polyneuritis, symmetrical mm wasting?
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dry beriberi
Thiamine, B1 deficiency |
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high-output cardiac failure, edema?
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wet beriberi
thiamine, B1 deficiency (dilated cardiomyopathy) |
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confusion, opthalmoplegia, ataxia, confabulation, personality change?
what is damaged? what is permanent effect? |
Wernicke-Korsakoff
Thiamine, B1 -damage to medial dorsal nucleus of thalamus, mammillary bodies -permanent memory loss |
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Vitamin B2 name? MOA?
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Riboflavin
cofactor in OXIDATION and REDUCTION (FADH2) -FAD & FMN are dervied from riboflavin |
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what vitamin is involved in oxidation and reduction?
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Vitamin B2, riboflavin
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vitamin deficiency - inflammation of lips, scaling and fissures at corner of mouth; vascularization of the cornea?
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Vitamin B2, riboflavin deficiency
2 Cs of B2 - cheliosis and corneal vasc. |
