Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
Oncogene: gain of function --> cancer
How many alleles need to be damaged? |
Only 1 allele of the oncogene needs to be damaged
|
|
|
CML:
|
abl, tyrosine kinase
|
|
|
Burkitt's Lymphoma:
|
c-myc , transcription factor
C-myc (not N-myc) |
|
|
Follicular and undifferentiated lymphomas:
|
bcl-2 , anti-apoptotic molecule
|
|
|
Breast, ovarian, gastric carcinomas:
|
erb-B2 , tyrosine kinase
|
|
|
Colon carcinoma:
|
ras , GTPase
|
|
|
Lung tumor:
|
L-myc , Transcription factor
(L for Lung) |
|
|
Neuroblastoma:
|
N-myc
(N for Neuroblastoma) |
|
|
MEN Type IIA and IIB
(also: Medullary Thyroid Carcinoma, Pheochromocytoma, and Parathyroid hyperplasia) |
ret , tyrosine kinase
|
|
|
Gastrointestinal Stromal Tumor (GIST)
|
c-kit , cytokine receptor
|
