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51 Cards in this Set

  • Front
  • Back
MS - Desensitizing and building system tolerance?
Mylin Basic Protein (MBP)
Example: Copaxone
Mechanism: acts as decoy for immune antibodies
MS - Disease modifying drugs?
1) Betaseron: interferon B Ib
2) Avonex: Interferon B Ia
3) Rebif: Interferon Beta Ia
MS - DMD admin'd intramuscularly once per week?
Avonex
MS - DMD admin'd subcutaneously 3X's per week?
Rebif
MS - DMD admin'd subcutaneously every other day?
Betaseron
MS - DMD that affects liver function and may cause cardiac problems?
Avonex
MS - Monoclonal Antibody Treatment
Tysabri
MS - Basic function of the Monoclonal Antibody Treatments?
Slows or stops immune cells from moving out of the blood stream into the CNS
MS - SideE of Tysabri?
HA, fatigue, depression, UTIs, joint pain, abdominal discomfort
CA drugs used to treat MS?
1) Rituxin
2) Novatrone
MS - mechanism of Rituxin?
Brings the beta cell count down to 0 which is thought to cause the sclerosis
What does one need to take in combination with Rituxin?
Strong corticosteroids to avoid severe allergic reactions
MS - CA drug given every 6 mos?
Rituxin
MS - CA drug given every 4 mos?
Novantrone
MS - SideE of Novantrone
1) Infections
2) Bone marrow suppression
3) Nausea, hair thinning and mouth sores
4) Cardiac conditions, liver problems
MS - drug that has a 12 dose lifetime max?
Novantrone
MS - for spasticity?
1) Baclofen
2) Zanaflex
MS - hypertonic mm.?
Botox or phenol blocks
MS - painful spasms?
Tegratol
MS - for pain?
Nuerontin
MS - for tremor?
Klonopin
MS - for cognitive issue?
Aricept
MS - for managing depression?
Zoloft or Paxil
MS - for fatigue?
Provigil
MS - for spastic bladders?
Ditropan
PK - 4 dopamine replacement drugs?
1) Levodopa
2) Sinemet: Carbodopa/levodopa
3) Sinemet CR
4) Stalevo: Sinemet + Entacapone
PK - 5 dopamine agonists?
1) Parlodel
2) Permax
3) Requip
4) Mirapex
5) Apokyn
PK - 3 neuroprotective agents (Monoamine oxidase inhibitors)
1) Selegiline
2) Rasagaline
4) Coenzyme Q10
PK - 3 anticholinergics?
1) Artane
2) Kemadrin
3) Cogentin
PK - COMT Inhibitors?
1) Tolcapone
2) Entacapone
PK - antiviral dopamine agonist for dystonia?
Amantadine
PK - for dementia?
Rivastigmine
PK - Tolcapone?
COMT Inhibitor
PK - Entacapone?
COMT Inhibitor
Prevents dopamine breakdown?
COMT Inibitors
PK - Artane?
Anticholinergic
PK - Kemadrin
Anticholinergic
PK - Cogentin
Anticholinergic
PK - Selegiline
M. O. I
PK - Rasagaline
M. O. I
PK - Coenzyme Q10
M. O. I.
Type of PK drug that blocks enzymes which break down dopamine.
Monoamine Oxidase Inhibitors
PK - Parlodel
Dopamine agonist
PK - Requip
Dopamine agonist
PK - Permax
Dopamine agonist
PK - Mirapex
Dopamine agonist
PK - Apokyn
Dopamine agonist
PK - Levodopa
Dopamine replacement
PK - Sinement
Dopamine replacement
PK - Sinemet CR
Dopamine replacement
PK - Stalevo
Dopamine replacement