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9 Cards in this Set
- Front
- Back
Inosine |
is sometimes present in the anticodon of a tRNA, and can form two hydrogen bonds with either C, U or A. Thus, a tRNA containing I in the first position of the anticodon can recognize three different codons.
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The mechanism of self-splicing of group I introns. |
An exogenous guanosine is required to initiate two transesterification steps, which releases the intron as a linear molecule
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Group II introns are commonly found |
in chloroplasts and in mitochondria of plants and fungi. No snRNPs are required, but otherwise the process is very similar to nuclear intron splicing. The folding of the RNA molecules provides the same function that is normally met by the spliceosome snRNPs.
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RNA editing occurs in some cells to |
change one or more bases in the transcript to generate the proper codon(s) for translation.
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Adenosine deaminase acting on RNA(ADAR) |
edits many human mRNAs
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C to U editing of the mRNA |
Happens by deamination-- for ApoB protein results in different length proteins in the liver and intestine. The shorter protein aids in absorption of lipids in the intestine. C to U editing is found in many transcripts in plant mitochondria and chloroplasts.
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RNA export and import from/to the nucleus throughthe nuclear pores is controlled by |
exportin and importin proteins and GTP. The exon junction complex isimportant inallowing export of only thosetranscripts that have already had introns removed. The EJC proteins stay bounduntil the mRNA is in the cytoplasm.
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combinational control |
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What do each of these mean? |
Enhanceosome, imprinting, gene dosage compensation (like with a Bar body), steroid hormone receptor, and insulators. |