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5 Cards in this Set
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Fibromyalgia is a syndrome. not a disease
cluster of pain .tenderness, swelling chronic widespread MSK pain multiple symmetric tender points fatigue, stiffness sleep disorders mood d/o |
PATHOGENESIS of Fibromyalgia
Intensity of pain response is Out of proportion to stimulus percieved Unpleasant sensory and emotional experiences associated with some actual tissue damage |
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Theories/ Hypothesis for
understanding Fibromyalgia Central nervous system sensitization CNS becomes hypersensitive to stimulus. Hyperesthesia??? Allodynia?? Is Pain and pressure pathways Involved?? Pre-existing condition Trigger Child abuse PTSD accident Lupus/any Infectious cause Hormones ?? excess cortisol from stress??????? |
Low Growth hormone
Increased substance P Increased receptor activity in the CNS e.g. NMDA receptor |
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Incidence Of Fibromyalgia.
2% of the US population 7 million americans Age onset- 27-37 woman> men (3%) (0,5%) Incidence increases with age |
Fibromyalgia may coexist with
SLE(lupus) (40%) IBS CTD |
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2/3rd's of patients get better over time
Illness duration can last 10-15 years |
Commonalities between FM and SLE
Up's and down's of severity Both have Triggers ( stress physical/emotional anxiety) Both have fatigue ,myalgia,stiffness |
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Agonising pain with Multiple Tender points.
A mild finger pressure can cause heightened pain levels beyond the local site |
Associated features-
Post exercise exertion retention of fluid parasthesia ( numbness tingling or heightened sensitivity) cognitive problems- mood d/o depression difficulty with memory,vocabulary sleep problems fatigue stiffness |
