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10 Cards in this Set

  • Front
  • Back
all carrier proteins have a Tm except for ____. why?
the carrier protein carrying Na. B/c aldosterone can upregulate it.
explain why we get edema in CHF
heart not f'ning as a pump --> low effective circulating volume --> therefore conserve salt (thus, retain water)
how Na (i.e. volume) is regulated (where are the sensors and what do they do?
VENOUS
1. atrial stretch sensors -> ANP (decreases ADH, decrease vascular resis)
2. nerves adjacent to pulm caps -> inhibit SNS

ARTERIAL
1. carotid and aortic baroreceptors --> natriuresis
2. renal BP --> natriuresis

CHEMORECEPTORS
sensor Na+ concentration rather than volume
3 ways AII will cause Na conservation
1. vasoconstrict efferent arteriole
2. Na reabsorp in PT
3. aldosterone upregulation
when i have a question with
CHF, what is the FIRST THING THAT SHOULD COME TO MIND?? that it is a ____
LOW VOLUME STATE!!!!!!
NO 's effects on Na regulation
cause natriuresis and diuresis SEPARATE from vasodilatory properties
if you lose your pituitary, will adh secretion be impaired? what about thirst
ADH secretion = impaired
thirst mech still intact (b/c controlled by hypothal)
non-osmotic stimuli for ADH release
"vp vend"
-vomiting
-pain
-volume depletion
-exercise
-narcotics
-drugs
in states of Na conservation, can excrete as little as ____ mmol/day of Na+
1-2 mmol/day
in states of Na excess, can excrete as much as ___ mmol/day
800 mmol/day