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19 Cards in this Set

  • Front
  • Back
IN Fentanyl initial dose for pt (a) <60 years and >60 kg
and (b) >60 years and/or <60 kg
(a) 200 mcg IN
(b) 100 mcg IN
IN Fentanyl initial volume for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) 0.66 mL + 0.1 mL rounded to nearest 0.05 mL
= 0.75 mL IN
(b) 0.33 mL + 0.1 mL rounded to nearest 0.05 mL
= 0.45 mL IN
IN Fentanyl subsequent dose for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) + (b) 25 - 50 mcg IN
IN Fentanyl subsequent volume for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) + (b) 0.08 - 0.16 mL + 0.1 mL rounded to nearest 0.05 mL
= 0.20 - 0.25 mL IN
IN Fentanyl max dosage for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) 400 mcg IN
(b) 200 mcg IN
IN Fentanyl repeat dose and timing for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) + (b) repeat up to 50 mcg IN @ 5/60 titrated to pain and side effects until max dose reached
IV Fentanyl indications
Unable to administer IN route and methoxyflurane not controlling pain
IV Fentanyl initial dose for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) + (b) 25 - 50 mcg IV (0.2 0.25 mL)
IV Fentanyl subsequent dose and timing for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) + (b) repeat 25 - 50 mcg IV (0.2 0.25 mL) @ 5/60 titrated to pain and side effects until max dose reached
IV Fentanyl max dose for pt (a) <60 years and >60 kg and (b) >60 years and/or <60 kg
(a) + (b) 200 mcg IV
Fentanyl presentation

100mcg/2mL glass ampoule


200mcg/1mL glassvial (IN use only)


600mcg/2 mL glass vial (IN use only)

Fentanyl pharmacology

A synthetic opioid analgesic
CNS effects


-depression leading to analgesia
-Respiratory depression leading to apnoea
-Dependence (addiction)


Cardiovascular effects


-Decreases conduction velocity through AV node

Metabolism
by the liver and excreted by the kidneys
PEI (4)
-Sedation to facilitate intubation
-Sedation to maintain intubation
-Drug facilitated intubation
-Analgesia IN/IV
CI (1)
Known hypersensitivity
Precautions (7)
1. Frail pts
2. Impaired renal/hepatic function
3. Respiratory depression eg COPD
4. Current asthma
5. Pts on MAOIs
6. Known addiction to opioids
7. Rhinitis, rhinorrhea or facial trauma (IN route)
Fentanyl routes
IV
IN
SE (4)
-Respiratory depression
-Apnoea
-Rigidity of the diaphragm and intercostal muscles
-Bradycardia
OPD
IV onset immediate
IV peak <5 min
IV duration 30 - 60 min
IN peak 2 mins