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85 Cards in this Set
- Front
- Back
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Herpes Simplex Virus |
Red papules to vesicles to ulcers |
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Herpes Simplex Virus |
Fever, malaise, tender inguinal nodes |
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Herpes Simplex Virus |
Cytopathic effect |
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Molluscum Contagiosum |
Pearly dome shaped papules with dimpled center with cellular center waxy core containing cytoplasmic viral inclusions |
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Candidiasis |
Disturbance of normal flora due to Diabetes Mellitus, antibiotics, pregnancy and compromised neutrophils |
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Candidiasis |
Pruritis, erythema, swelling , curd-like discharge |
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Trichomoniasis |
Yellow, frothy discharge, dysuria, dyspareunia |
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Trichomoniasis |
Strawberry Cervix |
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Bacterial Vaginosis |
Malodorous fishy vaginal discharge |
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Bacterial Vaginosis |
Superficial and intermediate cell covered by coccobaccili |
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Bacterial Vaginosis |
Caused by Gardnerella vaginalis causing premature labor |
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Chlamydia trachomatis |
Causes endometriosis in uterus and salphingitis in fallopian tube |
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Pelvic Inflammatory Disease |
Infection begins in vulva and vagina then ascends |
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Pelvic Inflammatory Disease |
Caused by Neisseria gonorrhea |
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Pelvic Inflammatory Disease |
Acute suppurative salphingitis to pyosalphinx to chronic salphingitis to salphingo-oophoritis to Tubo-ovarian abscess |
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Pelvic Inflammatory Disease |
Scarring or repair of tubal lumen and fimbriae causes infertility |
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Bartholin Cysts |
Bartholin gland infection to abscess to duct obstruction to cyst formation |
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Leukoplakia |
White plaques |
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Lichen Sclerosus |
Increased chance to develop SCCA |
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Lichen Sclerosus |
Porcrlain or parchment smooth white plaques or macules |
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Squamous Cell Hyperplasia |
Not a premalignant lesion with thock epidermis with no atypia |
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Squamous Cell Hyperplasia |
Due to scratching or rubbing of skin |
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Lichen Sclerosus |
Thin epidermis, degeneration of bqsal cells, hyperkeratosis , dermal band-like lymphocytic infiltrates |
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Skin Tag/Fibroepithelial Polyp/Squamous Papilloma |
Benign non-keratinizing squamous epithelium |
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Condyloma acuminatum |
Low oncogenic risk HPV 6 and 11 and not a pre-cancerous lesion |
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Condyloma acuminatum |
Tree-like cores covered by thickened epothelium with koilocytic atypia |
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Classic Vulvar Intraepithelial Neoplasia |
Reproductive age with thick epidermis, nuclear atypia, increased mitoses, lack cellular maturation |
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Differentiated Vulvar Intraepithelial Neoplasia |
Marked atypia with normal appearing superficial layer |
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Papillary Hidradenoma |
Similar with intraductal breast papilloma |
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Extramammary Paget Disease |
Pyuritic, red crusted, map-like appearance |
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Vaginal Intraepithelial Neoplasia |
Premalignant to SCCA |
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Squamous Cell Carcinoma |
1% of malignany neoplasms in Female Gential Tract associated with HPV at posterior upper vagina |
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Embryonal Rhabdomyosarcoma |
Less than 5 y/o with grape-like clusters |
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Cervicitis |
Increased pH leading to overgrowth of microorganism (gonococci, chlamydia, mycoplasma , hsv |
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Endocervical Polyps |
Bumps or polypoid mass with fibromyxomatous stroma covered by mucin secreting endocervical glands |
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Endocervical Polyp |
Main significance: bleeding |
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Human Papilloma Virus |
Infect immature basal cells of squamous epithelium |
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Human Papilloma Virus |
E6 and E7 viral proteins |
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Sertoli-Leydig Cell Tumor |
Masculinization and DICER1 mutation |
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Fibrothecoma |
Fibroblasts + plump spindle cells with lipid droplets (thecoma) |
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Fibroma |
Differentiated firboblasts with scant collagenous stroma |
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Meigs Syndrome |
Ovarian tumor + ascites + hydrothorax |
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Granulosa Cell Tumor |
Potentially malignant composed of cells that resemble granulosa cells of developing ovarian follicle |
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Choriocarcinoma |
Extraembryonic differentiation of germ cells and elaborates hCG |
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Transitional Cell Tumor |
Brenner tumor resembling urothelium |
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Cystadenofibroma |
Benign proliferation of the fibrous stroma |
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Clear Cell Carcinoma |
Similar genetic aberrations with endometrioid adenocarcinoma |
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Mucinous Tumor |
KRAS proto-oncogene mutation and mucin secreting |
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Yolk Sac Tumor |
2nd most common malignant germ cell tumor |
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Yolk Sac Tumor |
Elaborates a-fetoprotein |
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Yolk Sac Tumor |
Schiller Duval bodies |
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Dysgerminoma |
Counterpart of seminoma and malignant with gray-pink, soft , fleshy and vacuolated clear cytoplasm |
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Monodermal/Specializef Teratoma |
Struma Ovarii composed of thyroid |
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Mature Teratoma |
Most common germ cell tumor |
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Low Grade Serous Tumor |
KRAS, BRAF ERBB2 mutation |
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High Grade Serous Tumor |
TP53 mutation |
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Stromal Hyperthecosis |
Hypercellular luteinized stroma with striking virilization |
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Polycystic Ovarian Syndrome |
Hyperandrogenism, menstrual abnormalities, polycystic ovaries, chronic anovulation, decreased fertility |
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Polycystic Ovarian Syndrome |
Endometrial hyperplasia risk to carcinoma |
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Luteal Cyst |
Cyst lined of luteinized granulosa cells |
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Cystic Follicles |
Unruptured graafian follicle or ruptures but sealed immediately |
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Follicle Cyst |
>2cm cysts |
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Cystic Follicles |
With gray, glistening membrane, clear serous fluid |
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Paratubal Cyst |
0.1-0.2 cm fluid filled cyst with remnants of mullerian ducts |
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Hydatids of Morgagni |
Larger cysts, near the fimbria or in broad ligaments |
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Suppurative Salphingitis |
Gonococcus |
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Leiomyosarcomas |
From myometrium or stromal precursor cells |
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Leiomyosarcoma |
10 or more mitoses/10 HPO 5 mitoses/10 HPO with nuclear atypia or large epithelioid cells |
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Leiomyoma |
aka Fibrioids |
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Leiomyoma |
With interlacing bundles of smooth muscle cells that resemble normal myometrium with scarce mitosis |
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Adenosarcoma |
Benign glands, malignant stroma |
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Type I Endometrial Carcinoma |
Due to unopposed estrogen, obesity, hypertension and diabetes, precursor hyperplasia |
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Type II Endometrial Carcinoma |
Due to atrophy and thin physique from serous endometrial intraepithelial carcinoma |
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PTEN |
Encodes lipid phosphatase |
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Endometrial Hyperplasia |
Increased proliferation of glands relative to stroma and increased estrogenic stimulation |
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Endometrial Polyp |
Exophytic mass with glands may be atrophic, hyperplastic or with secretory activity |
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Endometrial Polyp |
With firbous stroma and thick-walled blood vessels enclosed with fibroblast |
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Adenomyosis |
Endometrial tissue within myometrium |
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Endometriosis |
Ectopic endometrial tissue causing infertility, dymenorrhea and pelvic pain |
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Chronic Endometritis |
Due to retained gestation tissue, miscarriage, IUD Tuberculosis |
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Chronic Endometritis |
With plasma cells in stroma in endometrium |
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Inadequate Luteal Phase |
Inadequate progesterone production after ovulation |
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Anovulatory Cycle |
Failure to ovulate with excessive estrogen stimulation, unopposed by progesterone |
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Dysfunctional Uterine Bleeding |
Bleeding that lacks underlying structural abnormality (chronic endometritis, polyp, leiomyoma) |
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Dysfunctional Uterine Bleeding |
Due to hormonal disorder |
