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22 Cards in this Set
- Front
- Back
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Cervicitis
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chronic disease occurs in most women of reproductive age and is of little consequence; occurs when squamous mucosal proliferation blocks glandular crypt openings, forming nabothian cysts; causes inflammation, ulceration, and repair; acute disease may be symptomatic and is caused by various sexually transmitted infections
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A.
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Endocervical Polyps
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B.
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Cervical Intraepithelial Neoplasia
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CIN I
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is a low-grade lesion involving disorganization and koilocytosis in the lower third of the epithelium, and often regress in immunocompetent hosts
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CIN II
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involves changes in two thirds of the epithelium
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CIN III
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occupies the entire epithelium and shows no maturation, frequently leading to invasive carcinoma and rarely showing regression
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Squamous Cell Carcinoma of cervix; epidemiology, risk factors
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one of the most common cancers in women, and a leading cause of death; occurs in middle adulthood; most commonly caused by HPV types 16 and 18
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squamous cell carcinoma of cervix morphology
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appears as an exophytic or ulcerated lesion with well-differentiated cells
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squamous cell carcinoma of cervix pathology
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spreads by invasion of local pelvic viscera and possibly to lymph nodes; morbidity and mortality occur by damage to local structures
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Adenocarcinoma of cervix
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accounts for a minority of cervical cancers caused by HPV types 16 and 18; carries a worse prognosis than squamous cell carcinoma
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Clear Cell Carcinoma of cervix
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occurs in women of early reproductive age; strongly associated with diethylstilbestrol exposure in utero
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Vaginal Intraepithelial Neoplasia
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involves non-invasive atypical squamous proliferation; represents a precursor lesion to malignancy
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Squamous Cell Carcinoma of vagina
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primary vaginal tumors are rare; mostly associated with HPV infection; lesions from the upper vagina spread to pelvic nodes, and ones from the lower vagina spread to inguinal nodes
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Adenocarcinoma of vagina
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rare tumor associated with prenatal exposure to diethylstilbestrol
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Embryonal Rhabdomyosarcoma (Sarcoma Botryoides)
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occurs in young children; grows as a polypoid mass in the vaginal lumen; composed of a hypercellular zone with loose myxomatous stroma; may invade locally and produce urinary obstruction
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Bartholin Gland Cysts
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result from obstruction of the Bartholin duct, usually caused by an abscess formation; may cause a mass lesion with pain
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Vestibulitis
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inflammation of glands at the posterior introitus causes ulceration and pain
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Leukoplakia
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describes various inflammatory and neoplastic disorders that cause white, scaly plaques on the vulva; may be caused by lichen sclerosis or squamous hyperplasia; requires a biopsy to rule out neoplasm
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Papillary Hidradenoma
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benign tumor arising from modified apocrine sweat glands on the labia majora
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Vulvar Intraepithelial Neoplasia
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non-invasive premalignant atypical squamous proliferation; related to HPV exposure
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Squamous Cell Carcinoma of vulva
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primary tumors are relatively rare on the vulva; younger women develop carcinoma in the context of infection by high-risk HPV types; older women tend to develop carcinoma with a background of lichen sclerosis or squamous hyperplasia, often with a worse prognosis in such cases
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Extramammary Paget’s Disease
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presents with itchy lesions on the labia majora; is frequently confined to the epidermis without an underlying carcinoma
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