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32 Cards in this Set

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  • Back
What are the top 4 noscomial infection sites?
1) Urinary Tract
2) Surgical Site
3) Lung
4) Blood stream
What are the main organisms that cause surgical site noscomial infections?
Gram + skin colonizers
1) S. aureus
2) CNS
3) enterococcus
What organisms cause noscomial pneumonia?
S. Aureus (outlier)
GRAM NEGATIVES (pseudomonas, actinobacter, enterobacter, klebsiella
How can noscomial pneumonia be prevented?
raise head of bed, avoid antacids, sedation vacation, reduce use of ventilators
What are the risk factors for noscomial bloodstream infection?
CVC USE!!
young or old age, malnutrition, IS therapy, loss of skin (burn), long stay at hospital
What organism causes lyme disease?
borrelia burgdorferi
what organism causes babesiosis?
babesia microti
what organism causes granulocytic anaplasmosis
anaplasma pagocytophilum
what organism causes RMSF?
rickettsia rickettsii
What is the distribution of Lyme Disease? What are its vectors associated with the area?
Western Seaboard: blacklegged tick
East Coast, Great Lakes: deer tick
*nymph is resp. for most disease
How long must a tick attach to spread Lyme dx? why?
at least 24 hours: to upregulate specific virulence genes to allow transmission from the tick into blood
What are the primary stage sx of lyme dx?
constitutional symptoms, erythema migrans occuring days to weeks after the bite
What is the secondary stage sx of lyme dx?
weeks post bite reflecting dissemination
dermatologic: EM at diff site
Cardiac: AV block
Neurologic: bell's palsy, meningitis
What are the tertitary sx of lyme dx?
months post bite:
Migratory Arthritis
Neuroborreliosis (memory, confusion, peripheral neuropathy etc)
What are the steps in diagnosing Lyme Dx?
1) Rash-is a clinical Dx!!
2) Elisa (if positive, confirm)
3) Immunoblot
*works similar to HIV testing
When do you need to use IV cetftriaxone (instead of doxycycline) to treat Lyme Disease?
Meningitis, cardiac manifestation, recurrent arthritis
(3-4 week duration with these sx)
What is the distribution of babesiosis
Same as Lyme disease: western seaboard and east coast, this makes coinfection very common!. *ALSO BY TRANSFUSION
What is the lab dx of babesiosis?
low Hg and platelets, evidence of hemolysis, blood smear shows intraerythrocytic ring fomrs, resembling malaria parasites
What is the treatment of babesiosis?
Atovaquone and azithromycin or quionine plus clindamycin. NOT similar to lyme disease, so consider testing for both
Where do anaplasmosis and ehrlichiosis infect?
WBC
What are the distributions of HGA and HME?
HGA: same as lyme: western seaboard and eastern USA
HME: South east corner of USA
What are the clinical manifestations of HME/HGA (they are the same)
fever, HEADACHE, myalgias, dry cough, rash
labs: leukopenia, elevated LFT, morulae
Where are RMSF cases found
have been reported in almost al states, most cases are in midwest and southeastern states
What are the sx of RMSF
fever, N/V, headache, myalgia,
rash (macular or petichial)
late sx: abdominal pain, joint pain, diarrhea
Most tick-associated infections are treated with...?
doxycycline (exception is babesiosis)
(tick borne diseases)
Failure to treat early with doxycycline is associated with high mortality rate in patients with...
RMSF
If a patient has an EM what test do you need to do next?
NONE
Ixodes scapularis (deer tick) can transmit what organisms
borrelia burgdorferi
anaplasma phagocytophilum (HGA)
babesia microti
*same distrubution *consider co-infections
What are the signs of LV enlargement?
PA: apex down and out
Lateral: LV projects out greater than 2 cms behind the IVC
What are the signs of LA enlargement?
double density sign as the left atrium elevates the left mainstem bronchus
What are signs of RV enlargement?
Boot shaped heart
lateral: right ventricle will fill in the retrosternal clear space
What are signs of RA enlargement?
Prominent right border