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53 Cards in this Set

  • Front
  • Back
What is the definition of an abortion in a cow?
The expulsion of a dead or non-viable calf before 260 days gestation.
What are the 3 most common abortive causes?
Neospora
Bacillus
Leptospira
What percent is the cut of for "allowable" levels of abortion?
5%
What bits of animal should be sent to the lab for abortion investigation?
Whole foetus
Placenta with cotyledons
Lesions and normal tissue
Maternal blood sample
If the whole foetus cannot be sent into the lab for investigation, what should be?
Aseptically collected foetal stomach contents
Pleural or peritoneal fluid
Liver
Lung
Thymus
Blood
Four categories of bovine infertility?
Functional
Anatomical
Infectious
Management
What is the campylobacter spp involved in abortion?
Campylobacter foetus var venerealis
How is CAMPY spread?
It's natural habitat is on the prepuce, glans penis and distal urethra of infected bulls. It gets spread through mechanical transmission.
What systemic disease do females infected with CAMPY get?
None except maybe a mild endometritis and cervicitis with a mucopurulent vag discharge.
Around what month do cows with CAMPY abort?
Around 4-7 months and have RFM; sometimes preg survives to term
Classically, what will a CAMPY cow present as?
A repeat breeder
Do cows dvp immunity to CAMPY?
Yes, after 3-6 months. Bulls are permanently infected.
How is CAMPY diagnosed?
Isolation from post-service discharges or bacterial culture of bull semen (or virgin heifer test)
What is the abortion rate for CAMPY?
Seldomly exceeds 10%
Sequellae of CAMPY infection?
Endometritis or salphingitis
Control of CAMPY?
AI stock
Run clean and dirty herds
Cull bulls
Treatment of CAMPY?
Females usually not tx but IU streptomycin or penicillin will shorten course of disease
If the farmer doesnt want to cull his CAMPY bull, what needs to occur before he can be used again?
Must have 4 negative virgin heifer tests or lab tests.
Is Brucella eradicated from UK?
Yes, 1983 but outbreaks have occured recently
How is BRUCELLA spread?
Ingestion - replicates in reg LN with a following bacteraemia followed by colonisation of supermammary LN, mammary gland and uterus. Hits uterus by 2nd trimester.
How does BRUCELLA cause abortion?
Placental disruption and endotoxaemia
Is BRUCELLA shed after abortion?
Yes, in fluids and faeces for about 3 weeks
What are the CS of BRUCELLA abortion?
No systemic disease - abortion is only real sign. Rarely there is mastitis and lameness and bulls can get orchitis.
Do cows dvp immunity to BRUCELLA?
No - usually only abort once but remain infected and excrete as carriers.
What are BRUCELLA foetuses like?
Can be born dead or alive - some have signs of bronchopneumonia
How is BRUCELLA diagnosed?
Serology and culture (milk, foetus, vagina)
Cotyledon smears (will find placentitis and necrotic thickened inter-c area).

Autolysis will obscure foetal lesions.
What does BHV-1 cause?
IBR, which causes respiratory disease, milk drop and abortion
How is IBR spread and what happens depending on time of infection?
Inhalation

If at service or AI can lead to repeaters or abortion
If later in preg may lead to stillborn or non-viable calves
What time is the cow most susceptible to IBR abortion?
5-6 months
What % of IBR cows experience repro issues?
50%
How is IBR eradicated?
Test and cull, as the virus can become latent and shed randomly when the animal is stressed.
What are foetal lesions like in IBR?
Renal haemorrhagic oedema
General organ necrosis
Thickened amnion
How is IBR diagnosed?
Virus isolation from placenta, ID of intranuclear inclusion bodies in foetal tissues or serum pairings
Vaccination for IBR?
Intra-nasal or IM with an annual or biannual booster
Main VIRAL causes of bovine abortion? Most important listed FIRST.
BVDV
BHV-1
PI3
Transmissible viral papillomatosis
Main BACTERIAL abortive causes in bovines.
Leptospira
Brucella
Campylobacter
Bacillus
Salmonella
Listeria
A. pyogenes
Briefly explain the NEOSPORA lifecycle.
Definitive hosts are dogs/foxes which shed oocysts in their faeces - these are picked up by moos. There is also vertical transmission from cow to calf! BIG DEAL.
What are the economic losses regarding NEOSPORA?
Loss of CALF
Milk loss
Culling increased
What is the month range for abortion in NEOSPORA?
3-8 months
What happens when cows are infected EARLY and LATE preg with NEOSPORA?
Early - later abortion
Late - full term, clinically normal carrier calf (PI!)
What happens when a PI animal in NEOSPORA cases gets preg?
Either abortion from month 3 on, stillbirth, alive calf with neuro signs OR a PI normal calf.
How is NEOSPORA diagnosed?
Pathology - non-inflam necrotic foci in CNS, bradyzoites in mycardium and liver, necrotic placental lesions
How is NEOSPORA controlled?
No vacc, no tx. Prevent canine-bovine contact. Can try culling seropositive cows or do nothing in low prevalence herds. You really cannot control completely.
Name a few RANDOM causes of abortion to consider.
Q fever
Aspergillus
Mycoplasma
Epizootic bovine abortion
How is BVD spread?
Mostly through direct contact with viraemic animals and inhalation or ingestion of virus. Fomites and AI tubes as well.
What happens when cows are infected with BVD under 110 days of gestation?
PI calf born bc of failure of foetus to recognise virus as foreign. Sometimes also see mummification and abortion.
What happens when cows are infected with BVD between 90-150 days gestation?
Usually congenital abnormalities as well as abortion.
What happens when cows are infected with BVD over 150 days?
Usually gives weak/premature calves as well as abortion.
When does abortion from LEPTO normally occur?
3-12 weeks following acute infection
How is LEPTO spread?
Bacterial penetration of mm or skin; venereally from bulls.

SHEEP are maintenance hosts!
What CS can LEPTO cause?
Abortion
Infertility
Milk Drop
What does the foetus look like in LEPTO?
Autolysed, icteric and oedematous.
Main types of LEPTO?
Leptospira interrogans serovar Hardjo
Leptospira borgspetersenii serovar Hardjo