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16 Cards in this Set
- Front
- Back
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Epoetin Alfa
Darbapoetin |
Ind: Chronic kidney
Sides: Thrombosis, Fe defic = supplemental Fe Monitor: Hematocrit |
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Sargramostim = GM-CSF
Filgrastim = G-CSF |
Stim granulocyte/macro
Ind: Marrowxplant, aplastic anemia, chemotherapy |
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Oprelvekin
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Form of IL-11
Increases magakaryo/platelet Ind: Thrombocytopenia Sides: fluid retention |
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Thrombopoetin
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Ind: Myelosuppression w/ thrombocytopenia
Sides: Ab to thrombopoeitin |
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Oral Iron
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4-7 days for response
Tox: Necrotizing enteritis w/ bloody diarrhea and shock |
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Folic acid
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High dose counter antiepileptic
Give if high Homocysteine |
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Heparin
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Instantly enhances antithrombin
decreased Thrombin, IXa, Xa Ind: VT, PE, aMI, bypass, DIC Sides: Osteoporosis, thrombocyto Monitor: aPTT, ACT HIT = IgG for heparin & IV |
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Enoxaparin
Dalteparin Other parins |
LMWH
Xa inhibitor Contra: Renal failure |
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Protamine Sulfate
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Neutralize heparin
Also an anticoagulant Anaphylactic in diabetic |
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Lepirudin
Bivalirudin Argatroban - liver metab |
Direct thrombin inhibitor
Ind: HIT, alternative to heparin Renal cleared |
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Danaparoid
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Mixture
Inhib Xa Ind: DVT prophylaxis, HIT |
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Drotrecogin alfa
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Protein C
Inactivates Va & VIIIa Decreased mortality in sepsis |
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Warfarin
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Antagonize K (II, VII, IX, X, C&S)
Binds to plasma protein Delayed effect/recovery Ind: Prevent DVT/PE/emboli afib Contra: Preg Monitor: INR/PT |
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Streptokinase
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Complex w/ plasminogen
Lysis fibrin clots Sides: Allergies |
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Alteplase
Reteplase Tenecteplase |
tPA
Clot specific Plasminogen act Ind: aMI, CVA, Occlusion, PE, prosthetic heart valve thrombosis Contra: Surgery, severe HTN, aortic dissection, Pericarditis |
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Aminocaproic acid
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Blocks plasmin from Fibrin
Ind: Tooth extraction, Prostate surg Risk: Excess thrombosis |
