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14 Cards in this Set
- Front
- Back
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Quinidine
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Block activated Na+, partial K+
Reduce Vmax P0 AP Hyperpolarizes membrane Slows Pacemaker of SA & Ectopic Ind: PAC, AVreentry, PVC, Vtach Flutter/Fib = combo digitalis Contra: CHF (-) inotropic |
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Procainamide = SLE
Disopyramide |
Block activated Na+, partial K+
Ind: SV (atrial), Vent arrhythmia Procainamide less antiACh OD give lactate Disopyramide combo digitalis |
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Lidocaine
Mexiletin = Oral Tocainide = Oral |
Block activated/inact Na+
Only effects damage/depol Decrease AP duration Ind: V arrhythmia from MI, Surg, digitalis induced arrhythmia |
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Phenytoin
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Block act/inact Na+, Ca2+
Ind: 2nd level V arrhythmia, V arrhythmia from pacemakers Sides: CNS |
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Flecainide
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Block act/inact Na+
Lower Vmax&rate Ind: drug resistant arrhythmias = PVC, Atrial fib Contra: Heart failure, Bblocker or Ca2+ blockers |
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Propafenone
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Block act/inact Na+, B block
Prevent resistant supraventricular arrhythmia |
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B blockers
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Prevention of ventricular arrhythmias arising from atrial arrhythmia
(atrial fibrillation or flutter) Contra: CHF |
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Bretylium
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Blocks NE release
Only in emergency for Vfib Also recurrent resistant tach Tox: Shock from hypotension |
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Amiodarone
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Block inact Na+, K+
Depress conduction in depol Prolong AP duration Slows automaticity Ind: Rapid SA = V arrhythmia Side: Eye, Skin, Thyroid |
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Dofetilide
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Block Kir (inward rectifier)
Prolong AP Made worse in hypokalemia Ind: Restore rhythm after Afib Tox: Long QT, torsade de pointes Causes arrhythmia in low K+ Creatine clearance for dose |
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Ibutilide
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Block Kir
Increase AP duration Ind: Aflutter, Afib Tox: Long QT, torsade de pointes |
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Verapamil
Diltiazem *Bucholz says diltiazem ok in CHF but Jutzy says not ok in CHF, wiki says do not use in CHF |
Ca2+ block
Ind: SVT caused by Atach/Afib Tox: reversed by Isoproterenol and calcium gluconate |
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Adenosine
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Rapid Kir activation, block Ca2+
Hyperpolarizes Causes short asystole Ind: Convert paroxysmal SVT to normal sinus rhythm Induces short AV block |
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Magnesium
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Alters Na+, K+, Ca2+
Used for Torsade de pointes Prevent Afib after cardiac surg |
