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23 Cards in this Set
- Front
- Back
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afferent arteriole
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blood flow to glomerulus
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efferent arteriole
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blood flow out of glomerulus
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which kidney taken during transplantation and why?
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left kidney b/c longer renal vein
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path of ureters
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Water (ureters) UNDER the bridge (artery, ductus deferens)
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ECF ions
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-more sodium
-less potassium |
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ICF ions
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-more potassium
-less sodium |
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TBW- ECF-
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ICF
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ECF- PV=
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interstitial volume
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60-40-20 rule
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% of body weight
-60% total body water -40% ICF -20%ECF |
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plasma volume measured how
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by radiolabeled albumin
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extracellular volume measured by
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inulin
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renal clearance
1. equation 2. what is it? 3. units 4. Cx < GFR 5. Cx > GFR 6. Cx=GFR |
1. UxV/Px
2. volume of plasma from which the substance is completely cleared per unit time 3. mL/min 4. net tubular reabsorption of X 5. net tubular secretion of X 6. no net secretion or reabsorption |
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1. Cx is
2. Ux is 3. Px is 4. V= |
1. clearance of X (mL/min)
2. urine concentration of X 3. plasma concentration of X 4. urine flow rate |
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glomerular filtration barrier
1. function |
responsible for filtration of plasma according to size and net charge
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glomerular filtration barrier composed of:
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-fenstrated capillary endothelium (size barrier)
-fused basement membrane with heparan sulfate (negative charge barrier) -epithelial layer consisting of podocye foot processes |
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what is lost in nephrotic syndrome? what results?
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1. the charge barrier of glomerular filtration barrier is lost
2. albuminuria, hypoproteinemia, generalized edema, and hyperlipidemia |
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used to calculate GFR? why?
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inulin; b/c it is freely filtered and is neither reabsorbed nor secreted
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what is an approximate measure of GFR
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creatinine clearance
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GFR=
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=(Uinulin x V)/ (Pinulin)= Cinulin= GFR
=Kf [(Pgc-Pbs)- (PIEgc- PIEbs)] |
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how is PIEbs
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normally equals zero
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Effective renal plasma flow (ERPF)
1. can be estimated using? why? 2. calculation |
1. using PAH clearance b/c it is both filtered and actively secreted in proximal tubule (All PAH entering kidney is excreted)
2. ERPF= Upah xV/Ppah= Cpah |
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RBF=
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RPF/ (1- Hct)
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how are ERPF and RPF relatedq
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ERPF underestimates true RPF by 10%
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