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6 Cards in this Set
- Front
- Back
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The following HLA subtypes are associated with what pathological findings...?
1. B27 2. B8 |
1. Psoriasis
Ankylosing spondylytis Inflammatiry bowel disease Reiter's Syndrome "PAIR" 2. Graves disease, celiac sprue |
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The following HLA subtypes are associated with what pathological findings...?
1. DR2 2. DR3 3. DR4 4. DR5 5. DR7 |
1. Multiple sclerosis, hay fever, SLE, good Pasteures
2. Diabetes Mellitus Type I 3. Rheumatoid Arthritis, daibetes mellitus type 1 4. Pernicious anemia -> B12 deficiency, Hashimotos thyroiditis 5. Steroid responsive neprhotic syndrome |
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What are the major diagnostic uses for the following enzyme markers...?
1. Aminotransferases (AST/ALT) 2. GGT (y-guanyl transferase) 3. Alkaline phosphatase 4. Amylase |
1. myocardial infarction (AST only)
Viral hepatitis (ALT>AST) Alcoholic hepatitis (AST> ALT) 2. various liver diseases 3. bone disease (Paget's bone disease), obstrucive liver disease (hepatocellular carcinoma) 4. acute pancratitis, mumps |
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What are the major diagnostic uses for the following enzyme markers...?
1. lipase 2. CPK 3. LDH-1 (lactate dehydrogenase function) 4. Ceruloplasmin (decreased levels) |
1. acute pancreatitis
2. muscle disorders (eg. Duchennes muscular dystrophy) and MI (CPK-MB) 3. MI (LDH-1> LDH-2) 4. Wilson's disease |
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What pathological findings are associated with the following amyloid deposits...?
1. AL 2. AA |
1. Amyloid light chain; seen in plasma cell dyscrasias (multiple myeloma, Waldenstrom's); often fatal
2. From serum amyloid associated protein, acquired secondary to chronic inflammatory disorder; familial variants exist |
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What pathological findings are associated with the following amyloid deposits...?
1. ATTR 2. AB (beta) 3. B2 microglobulin |
1. from transthyretin, a serum transport protein; familial and acquired in the elderly
2. major compnent of Alzheimers plaques 3. deposits in tendons and joints of dialysis patients |
