Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
22 Cards in this Set
- Front
- Back
|
neuroectoderm gives rise to what
|
CNS neurons, ependymal cells, oligodendroglia, astrocytes
|
|
|
neural crest gives rise to what
|
schwann cells
PNS neurons |
|
|
mesoderm gives rise to what
|
Microglia
Macrophages |
|
|
Nissl substance where
|
from RER in cell body, dendrites, NOT axon
|
|
|
function of astrocytes
|
physical support, repair K metabolism, removal of excess NT, maintain BBB
|
|
|
astrocyte marker
|
GFAP
|
|
|
microglia
1. are what? 2. origin 3. HIV infected microglia 4. tissue damage causes |
1. CNS phagocytes
2. mesoderm 3. multinucleated giant cells in the CNS 4. large ameboid phagocytic cells |
|
|
oligodendroglia
1. where 2. predominant type of glial cells in what 3. destroyed in what disease 4. looks like what on H and E |
1. myelinates multipleCNS axons
2. white matter 3. multiple sclerosis 4. fried eggs |
|
|
Schwann cells
1. are what? 2. promotes what? 3. derived from what? 4. destroyed in what disease? |
1. myelinates only 1 PNS axon
2. axonal regeneration 3. neural crest 4. Gullian-Barre syndrome |
|
|
Acoustic neuroma
|
-type of schwannoma
-typically located in internal acoustic meatus (CN VIII) |
|
|
free nerve endings
(C, alphabeta fibers) 1. location 2. senses |
1. all skin, epidermis, some viscera
2. pain and temp. |
|
|
Meissner's corpuscles
1. location 2. senses |
1. Glabrous (hairless) skin
2. dynamic fine touch (ex. manipulation, adapt quickly |
|
|
Pacinian corpuscles
1. location 2. senses |
1. deep skin layers, ligaments, and joints
2. vibration, pressure |
|
|
Merkel's disks
(cup-shaped, unencapsulated) 1. location 2. senses |
1. hair follicles
2. static touch ex. shapes edges, textures -adapt slowly |
|
|
Peripheral nerve layers
|
inner to outer
(endoneurium, perineurium, epineurium) |
|
|
endoneruium
|
invests single nerve layer
|
|
|
perineurium
|
Permeability barrier
-surrounds a fascicle of nerve fibers -must be rejoined in microsurgery from limb reattachment |
|
|
epineurium
|
dense connective tissue that surrounds entire nerve (fascicles and blood vessels)
|
|
|
NE
1. change in disease 2. location of synthesis |
1. increase in anxiety, decrease in depression
2. locus ceruleus |
|
|
Dopamine
1. change in disease 2. location of synthesis |
1. increase in schizophrenia, decrease in Parkinson's
2. ventral tegmentum and SNc |
|
|
5-HT
1. change in disease 2. location of synthesis |
1. decrease in anxiety, depression
2. Raphe nucleus |
|
|
ACh
1. change in disease 2. location of synthesis |
1. decrease in Alzheimer's, Huntington's
2. Basal nucleus of Meynert |
