Fa Immunology

Front 1

Lymph node

Back 1

A 2° lymphoid organ that has many afferents, 1 or more efferents. Encapsulated, with trabeculae.
Functions are nonspecific filtration by macrophages, storage of B and T cells, and immune
response activation.

Hint 1

What are its functions

Front 2

Lymph node: Follicle

Back 2

Site of B-cell localization and
proliferation. In outer cortex. 1° follicles
are dense and dormant. 2° follicles have
pale central germinal centers and are
active.

Hint 2

primary and secondary follicle functions.
Site of what

Front 3

Lymph node: Medulla

Back 3

Consists of medullary cords (closely
packed lymphocytes and plasma cells)
and medullary sinuses. Medullary
sinuses communicate with efferent
lymphatics and contain reticular cells
and macrophages

Hint 3

Consists of
Contains

Front 4

Lymph node: Paracortex

Back 4

Houses T cells. Region of cortex between
follicles and medulla. Contains high
endothelial venules through which T
and B cells enter from blood. Not well
developed in patients with DiGeorge
syndrome.

Hint 4

Houses
contains
Not well developed in patients with

Front 5

Thymus

Back 5

Site of T-cell differentiation and maturation.
Encapsulated. From epithelium of 3rd
pharyngeal pouches. Lymphocytes of
mesenchymal origin. Cortex is dense with
immature T cells; medulla is pale with mature
T cells and Hassall corpuscles containing
epithelial reticular cells.

Hint 5

Site of
From what pharyngeal pouch
Contents of cortex
contents of medula
Hassal corpuscles