Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/35

Click to flip

35 Cards in this Set

  • Front
  • Back
What is poorly developed in DiGeorge's syndrome?
paracortex
What drains the right arm and right half of head?
Right lymphatic duct
What drains most of the body's lymph?
thoracic duct
Where are T cells found in the spleen?
PALS, red pulp
What occurs at the corticomedullary junction of the spleen?
Positive and negative selection
3 major functions of antibody-mediated immunity?
Host defense against infection (opsonize bacteria)
Allergy (type I)
Autoimmunity
4 major function sof cell-mediated immunity?
Host defense agaisnt infection (TB, viruses, fungi)
allergy (type IV)
graft and tumor rejection
regulation of Ab response
All nucleated cells have MHC __
MHC I
All antigen-presenting cells have MHC ____
MHC I,II
Class __ are the main determinants of organ rejection
Class I
ANA
SLE
Anti-dsDNA, anti-Sm
specific for SLE
Antihistone
drug-induced lupus
Anti-IgG (rheumatoid factor which is IgM)
Rheumatoid arthritis
Antineutrophil (C-ANCA, P-ANCA)
Vasculitides
Anticentromere
Scleroderma (CREST)
Anti-Scl-70
Scleroderma (Diffuse)
Anti-mitochondrial
primary biliary cirrhosis
Antigliadin
Celiac disease
Anti-basement membrane
goodpasture's syndrome
anti-epithelial cell
pemphigus vulgaris
antimicrosomal and antithyroglobulin
hashimoto's thyroiditis
Anti-Jo-1
polymyositis, dermatomyositis
B27
PAIR
Psoriasis
Ankylosing Spondyliasis
Inflammatory Bowel Disease
Reiter's syndrome
B8
Gravy and Chili in Line 8
Graves' disease
Celiac sprue
DR2
Mary's Hens are So Good
Multiple Sclerosis
Hay fever
SLE
Goodpasture's syndrome
DR3
DM I
DR 4
Rheumatoid arthritis, DM I
DR 5
Hashimoto's thyroiditis, Pernicious anemia
DR 7
Steroid-responsive nephrotic syndrome
Antibody mediated due to presence of preformed antidonor Abs in transplant recipient. Occurs within minutes after transplantation.
Hyperacute rejection.
Cell mediated due to Tc against foreign MHCs. Weeks after transplantation. Reversible with immunosuppresants like cyclosporin and OKT3
Acute rejection
Antibody-mediated vascular damage. Months to years after transplantation. Irreversible.
Chronic rejection.
Grafted immunocompetent T cells proliferate in irradiated immunocompromised host and reject cells with "foreign" proteins.
Graft-vs-host disease
Maculopapular rash, jaundice, hepatosplenomegaly, and diarrhea.
Graft-vs-host disease