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163 Cards in this Set

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A woman with anxiety about a gynecological exam is told to relax and to imagine going through the steps of the exam. What process does this exemplify?
systematic desensitization
63 year-old man is diagnosed with incurable metastatic pancreatic adenocarcinoma. His family asks you, the doctor, not to tell the pt. What do you do?
Assess whether telling the pt will negatively affect his health. If not, tell him.
A man admitted for chest pain is medicated for ventricular tachy. The next day he jumps out of bed and does 50 push ups to show nurses he has not had a heart attack. What defense mechanism is he using?
Denial
You find yourself attracted to your 26-year-old patient. What do you say?
Nothing and invite a chaperone into the room if you feel your actions may be misinterpreted
A large group of people is followed over 10 years. Every two years, it is determined who develops heart disease and who does not. What type of study is this?
Cohort study
A girl can groom herself, hop on one foot, and has an imaginary friend. How old is she?
4
A man has flashbacks about his girlfriend's death 2 months ago following a hit-and-run accident. He often cries and wishes for the death of the culprit. What is his diagnosis?
Normal bereavement
A 36-year-old woman with a strong family hx of breast cancer refuses a mamogram because she heard it hurts. What do you do?
discuss risks and benefits; each pt must give consent so if the pt refuses, you must abide by her wishes
A 4-year-old girl complains of a burning feeling in her genitalia; otherwise, she behaves and sleeps normally. Smear of the discharge shows N. gonorrhoeae. How was she infected?
Sexual abuse
A 72-year-old man insists on stopping treatment for his heart condition because it makes him feel "funny." What do you do?
The pt has the final say in his tx, but you should investigate the "funn"y feeling and see if there are other drugs that do not illicit this response
During a particular stage of sleep, a pt has variable blood pressure, penile tumescence and variable EEG. What stage of sleep is he in?
REM sleep
Comparing a group of people with a disease to a group of people without the disease is an example of what type of study?
Case-control study: observational retrospective
What types of measures are more common in retrospective case-control studies?
Odds ratio (OR): Pts with COPD had higher odds of a hx of smoking than pts without COPD
Comparing a group with a given risk factor to a group without in order to assess whether the risk factor increased the likelihood of disease is an example of what type of study?
Cohort study: observational prospective
What types of measures are more common in propsective cohort studies studies?
Relative Risk (RR): "smokers had a higher risk for COPD than did nonsmokers"
Collecting data from a group of people to assess frequency of disease (and related risk factors) at a particular point in timeis an example of what type of study?
Cross-sectional study: observational
Can cross-sectional studies prove causality of a risk to a disease?
No. it can only show a risk factor association with a disease
Comparing the frequency with which both monozygotic twins or both dizygotic twins develop a disease is an example of what type of study?
twin concordance study
Twin concordance studies measure what aspect of disease?
heritability
Comparing siblings raised by biologic vs. adoptive parents is an example of what type of study?
Adoption study
Adoption studies measure what aspects of disease?
heritability plus environmental influences
What type of study is of the highest quality?
Randomized, double-blind, clinical trial
What is the study sample and purpose of a Phase I clinical trial?
small # of pts, usually nml volunteers; assess safety, toxicity, and pharmacokinetics
What is the study sample and purpose of a Phase II clinical trial?
small # of pts with dz of interest; assess tx efficacy, optimal dosing, and adverse effects
What is the study sample and purpose of a Phase III clinical trial?
lg # of pts randomly assigned to either tx, best available tx, or placebo; compare new tx to current standard of care
What is the purpose of a metaanalysis?
Pools data from several studies; acheives greater statistical power and integrates results of similar studies
How do you calculate prevalence?
Prevalence =total cases in a population at a given time/total population at risk
How do you calculate incidence?
Incidence = new cases in a population ove a given time period/total population at risk during that time
Incidence is new incidents
What is the general relationship between prevalence and incidence for chronic diseases (e.g., diabetes)?
Prevalence > incidence
What is the general relationship between prevalence and incidence for acute diseases (e.g., ommon cold)?
prevalence = incidence
The sensitivity of a test is a measure of what?
the percent of people with the dz who test positive
A high sensitivity value is desirable for what diagnsotic decisions?
Desirable for ruling-out dz
SNOUT=SeNsitivity rules OUT
Using the 2x2 table comparing test results ro actual presence of disease, how do you measure sensitivity?
a/(a+c)
The specificity of a test is a measure of what?
Percent of people without the disease who test negative
A high specificity value is desirable for what diagnsotic decisions?
desirable for ruling-in a disease
SPIN=Specificity rules IN
Using the 2x2 table comparing test results ro actual presence of disease, how do you measure specificity?
d/d+b
A positive predictive value (PPV) measures what?
Percent of positive test results that are true-positives
Using the 2x2 table comparing test results ro actual presence of disease, how do you measure positive predictive value?
a/(a+b)
A negative predictive value measures what?
Percent of negative results that are true-negative
Using the 2x2 table comparing test results ro actual presence of disease, how do you measurenegative predictive value?
d/d+c
How do you measure the Odds Ratio and for which studies are Odds Ratios used?
Odds of having a dz in exposed group/odds of having dz in unexposed group; case control studies
How do you measure the relative risk and for which studies are relative risks used?
Relative probablility of getting the dz in exposed group versus the unexposed group; cohort studies
What is the attributable risk?
The differenc in risk between exposed and unexposed groups; the % of dz occurences that are the result of exposure
Using the 2x2 table comparing risk factor to disease, how do you calculate odds ratio?
OR=(a/b)/(c/d)=ad/bc
Using the 2x2 table comparing risk factor to disease, how do you calculate relative risk?
RR=[a/(a+b)]/[c/(c+d)]
Using the 2x2 table comparing risk factor to disease, how do you calculate attributable risk?
AR=(a/a+b)-(c/c+d)
What is the difference between precision and accuracy?
precision is the consistence and reproducibility of a test and the absence of random variation; accuracy is the trueness of the test measurements
In general, what is bias?
When one outcome is systematically favored over another outcome
What are the four categories of bias?
1. Selection bias (nonrandom) 2. Recall bias 3. Sampling bias (nonrepresentative subjects) 4. Late-look bias (inappropriate time)
What are four ways to reduce bias?
1. blind studies 2. placebo responses 3. crossover studies 4. Randomization
What does a null hypothesis state?
That there is no association between the dz and the risk factor in the population
What is a Type 1 error (a)?
Stating that there is an effect or difference when none exists (to reject the null hypothesisby mistake)
What does a p value measure?
the percent chance that the data will show something that is not really there
What should a p value be in order to be statistically significant?
p<.05
If you are making a Type II (β) error, what are you doing?
You stated that there is not a differencewhen one exists (fail to reject the null hypothesis when the null is false)
When would you use a t-Test vs. ANOVA vs. x2
t-Test = checks the difference between the means of 2 groups; ANOVA = checks the difference between the means of 3 or more groups;x = difference between 2 or more percentages or proportions of categorical outcomes
Which diseases are reportable?
Hep B, HepA, Salmonella, Shigells, Syphilis, Measels, Mmps, AIDS, Rubella, TB, Chicken Pox, Gonorrhea
eveything you can get from sex and your childhood immunizations
What is the difference between Medicare and Medicaid?
Medicare is for the elderly, medicaid is for the low income people
What are the three levels of disease prevention?
1'=prevent dz occurrence (vaccines); 2'=early detection of dz 3'=reduce disability from dz
PDR = prevent, detect, reduce disability
What are the leading causes of death in infants?
congential abnormalities, premies/low birth weight, SIDS, maternal complications of pregnancy, respiratory distress syndrome
What are the leading causes of death in 1-14 year olds?
Injuries, cancer, congenital, homicide, heart dz
What are the leading causes of death in 15-24 year olds?
injuries, homicide, suicide, cancer, heart dz
What are the leading causes of death in 25-64 year olds?
cancer, heart dz, injuries, suicide, stroke
What are the leading causes of death in 65+ year olds?
heart dz, cancer, stroke, COPD, pneumonia, flu
What are the core ethical principles of medicine?
Autonomy, beneficence (act in the pts best interest); nonmaleficence (do no harm); Justice (treat all fairly)
In order to obtain informed consent, what three things are legally required?
1. discussion of pertinent information, 2. Pt's agreement to plan of care, 3. Freedom from coercion
What are the four exceptions to informed consent?
1. pt lacks decision making capacity 2. implied consent in an emergency 3. therapeutic privilege 4. Waiver
What are the 5 criteria for decision-making capacity?
1. pt makes and communicates choice, 2. pt is informed, 3. Decision remains stable over time, 4. decision is consistent with pt's values and goals, 5. decision is not a result of delusions or hallucinations
What is an oral advanced directive?
incapacitated pt's prior oral statements commonly used as a guide. Problems arise in interpretation.
What are the two most common types of written advanced directives?
Living will and Durable Power of Attorney
What are the four exceptions to confidentiality?
1. potential harm to others, 2. likelihood of harm to self, 3. no alternative means exist to protect those at risk, 4. physicians can take steps to prevent harm
What are the four criteria to file a civil suit of malpractice?
1. physician had a Duty ot the pt, 2. Physician breached the duty, 3. patient suffers harm, 4. the breach of the duty is what caused the harm
Four D's: duty, dereliction, damage, direct
What is the most common factor leading to litigation?
poor communication between physician and pt
What is the appropriate response to the follwing wthical situation: pt is noncompliant?
work to improve the physician-pt relationship
What is the appropriate response to the follwing wthical situation: pt has difficulty taking medications?
provide written instructions; attempt to simplify tx regimens
What is the appropriate response to the follwing wthical situation: family members ask for info about pt's prognosis?
avoid discussion issues with relatives without the permission of the pt
What is the appropriate response to the follwing wthical situation: 17-year old girl is pregnant and requests an abortion?
many states require parental consent; NOT required for an emergency/tx of STDs/medical care during pregnancy/management of drug addiction
What is the appropriate response to the follwing wthical situation: terminally ill pt requests physician assistance in ending his life?
in most states, refuse invovlement in any form of phys-assisted suicide; can give medically appropriate analgesics that coincidently shorten a person's life
What is the appropriate response to the follwing wthical situation: pt states that he/she finds you attractive?
Ask direct, closed-ended questions and use a chaperone, if necessary. Never appropriate to get romantically involved with a pt
What are the motor and cognitive milestones for the following age group: 24-48 mos?
parallel play
What are the motor and cognitive milestones for the following age group: 24-36 mos?
core gender identity
What are the motor and cognitive milestones for the following age group: 30-36 mos?
stacks 9 blocks; toilet training
What are the motor and cognitive milestones for the following age group: 3 yrs?
rides trike, copies line or circle drawing; group play
What are the motor and cognitive milestones for the following age group: 4 yrs?
simple drawings, hops on one foot; cooperative play, imaginary friends, grooms self, brushes teeth
What are the motor and cognitive milestones for the following age group:6-11 yrs?
reads, understands death; development of conscience, same sex friends, identification with same sex parent
What are the motor and cognitive milestones for the following age group: 11 yrs, girls?
Abstract reasoning, formation of personality
What are the motor and cognitive milestones for the following age group: 13 yrs (boys)?
Abstract reasoning, formation of personality
What are the five Tanner stages of sexual development?
1. childhood, 2. pubic hair beigns to develop, increased testes size, breast tissue elevation, 3. increased pubic hair, darkens, becomes curly, increase penis size/length, 4. increased penis width, glans, raise areola, 5. adult (areola no longer raised)
What are the characteristics of normal grief? How long does it last?
shock, denial, guilt and somatic symptoms; lasts 6 months to 1 year
What are the Grief stages?
Denial, anger, Bargaining, Greiving, Acceptance
Death Arrives Bringing Grave Adjustments
What is the differential diagnosis for sexual dysfunction?
Drugs (anti-HTN, neuroleptics, SSRI's, ethanol), Diseases, Psychological (performance anxiety)
How does one calculate BMI?
weight in kg/(ht in meters)^2
What are the BMI ranges for underweight, nl, overweight and obese, respectively?
< 18.5; 18.5-24.9; 25.0-29.9; >30.0
What type of EEG wave form will you have if you are awake with your eyes closed?
alpha
How much of a young adult's time is spent in light sleep?
5%
How much of a young adult's time is spent in deeper sleep (one level deeper than light sleep)?
45%
How much of a young adult's time is spent in deepest, non-REM sleep?
25%
How much of a young adult's time is spent in REM sleep?
25%
At which stage of sleep does one experience sleepwalking, night terrors and bed wetting?
Deepest, non-REM sleep
At which stage of sleep does one experience dreaming, loss of motor tone, erections and increased O2 brain use?
REM sleep
What type of EEG wave form will you have if you are in REM sleep?
Beta waves
Same as if you are awake
What class of drugs reduce stage 4 (deep non-REM) sleep and are thus good for treating sleepwalking and night terrors?
Benzos
What drug is used to treat enuresis by decreasing stage 4 sleep?
Imipramine
The activity of the PPRF (paramedian pontine reticular formation/conjugate gaze center) is responsible for what patter during sleep?
the extraocular movements during REM sleep
T/F: NE induces REM sleep
False: NE reduces REM sleep
What are the signs of narcolepsy (aside from just being asleep at awkward times)?
hypnogogic or hypnopompic hallucinations; sleep starts with REM sleep; cataplexy may occur
What is the tx for narcolepsy?
stimulants (amphetamines)
What is the mean IQ?
100 with a st deviation of 15
What are the IQ criteria for a dx of mental retardation, severe MR, profound MR, respectively?
<70, <40, <20
What is an example of "classical conditioning"?
Pavlov's doga natural response (salivation) is elicited by a learned stimulus (bell ring) that previously was presented in conjunction with an unconditioned stimulus (food)
What is operant conditioning?
learning in which a particular action is elicited because it produces a reward
Define positive reinforcement.
desired reward produces action (mouse presses button to get food)
Define negative reinforcement.
removal of adverse stimulus increases behavior (mouse presses button to avoid shock)
Which form of reinforcement is associated with a rapidly extinguished behavioral response: continuous or variable ratio?
Continuous
Think vending machine: you stop using if it does not deliver vs. Slot Machine: continue to play even if it rarely rewards
What is transference?
When a pt projects feelings about formative or other important persons onto a physician
psychiatrist = parent
What is countertransference?
when the dr projects feelings about a formative or other important persons onto the pt
What are Freud's 3 structures of the mind?
Id, Ego, Superego
What characteristics are commonly associated with the Id?
Primal urges, sex and aggression
What characteristics are commonly associated with the Ego?
mediator between unconscious mind and external world; deals with the conflict between Id and Superego
What characteristics are commonly associated with the Superego?
Moral values, conscience
What is the Oedipus Complex?
repressed feelings of a child for the opposite-sex parent, accompanied by rivalry with same sex parent
What are ego defenses, in general?
automatic and unconscious reactions to psychological stress
What are the 4 mature ego defenses?
Altruism, Humor, Sublimation, Suppression
SASH
Extreme forms of this immature ego defense are seen in multiple personality disorders.
Dissociation: temporary, drastic change in personality, memory, consciousness, or motor behavior to avoid emotional stress
A mother yelling at her child because she is angry at her husband is an example of which immature ego defense?
displacement
An abused child becoming an abuser is an example of which immature ego defense?
identification
Describing a murder in graphic detail with no emotional response is an example of which immature ego defense?
Isolation: separation of feelings from ideas/events
What is the appropriate response to the follwing ethical situation: pt states that he/she finds you attractive?
Ask direct, closed-ended questions and use a chaperone, if necessary. Never appropriate to get romantically involved with a pt
What is the appropriate response to the follwing ethical situation: pt refuses a necessary procedure or requests an unnecessary one?
attempt to understand why the pt wants/refuses the procedure. Address underlying concerns. Avoid performing unnecessary procedures
What is the appropriate response to the follwing ethical situation: pt is angry about the amount of time spent in the waiting room?
apologize; stay away from efforts to explain the delay
What is the appropriate response to the follwing ethical situation: pt is upset with the way he was treated by another doctor?
suggest that the pt speak directly to that dr regarding his concerns
What is the appropriate response to the follwing ethical situation: a child wishes to know more about his illness?
ask what the parents have told him; parents of a child decide what information can be relayed about the illness
What is the appropriate response to the follwing ethical situation:pt continues to smoke, believing cigarettes are good for him?
ask how the pt feels about his smoking; offer adivce on cessation is the pt seems willing to make an effort to quit
What is the appropriate response to the follwing ethical situation: pediatric pt requests condoms?
physicians CAN provide consultaiton and contraceptives to minors without a parent's knowledge or consent
When are AGPAR scores evaluated?
10 point scale at 1 minute and 5 minutes after birth
What does AGPAR measure?
Appearance, Pulse, Grimace, Activity, Respiration
What is a low birth weight defined as?
< 2500g
What are the motor and cognitive milestones for the following age group: 3 mos?
Holds head up, disappearance of moro reflex; social smile
What are the motor and cognitive milestones for the following age group: 4-5 mos?
rolls front to back, sits when propped; recognizes people
What are the motor and cognitive milestones for the following age group: 7-9 mos?
sits alone, crawls; stranger anxiety, orients to voice
What are the motor and cognitive milestones for the following age group: 12-14 mos?
Upgoing babinski sign disappears
What are the motor and cognitive milestones for the following age group: 15 mos?
walks; few words, separation anxiety
What are the motor and cognitive milestones for the following age group: 12-24 mos?
climbs stairs, stacks 3 blocks; object permanence
A patient with libidinous thoughts entering a monastery is an example of which immature ego defense?
reaction formation
A pt stating that all nurses are cold and unfriendly while all drs are warm and sensitive is an example of which immature ego defense?
splitting: belief that people are all good or all bad
A man who wants another woman thinking his wife is cheating on him is an example of which immature ego defense?
projection: an unacceptable internal impulse is attributed to an external source
Which ego defense mechanis is characterized by alleviating guily feelings by unsolicited gerosity towards others?
altruism
Which ego defense mechanis is characterized by appreciating the amusing nature of an anxiety-provoking or adverse situation?
humor
Which ego defense mechanis is characterized by the replacement of an unacceptable wish with a course of action that is similar to the wish but does not conflict with one's value system?
sublimation
Which ego defense mechanis is characterized by voluntary witholding of an idea of feeling from conscious awareness?
suppression
Which ego defense mechanis is characterized by unacceptable feelings and thoughts expressed through actions?
acting out
Which ego defense mechanis is characterized by temporary, drastic changes in personality, memory, consciousness or motor behavior to avoid emotional stress.
dissociation
Which ego defense mechanis is characterized by avoidance of awareness of some painful reality?
denial
Which ego defense mechanis is characterized by a process whereby avoided ideas and feelings are transferred to some neutral person or object?
displacement
Which ego defense mechanis is characterized by partially remaining at a more childish level of development?
fixation
Which ego defense mechanis is characterized by modeling behavior after another person who is more powerful (though not necessarily admired)?
identification
Which ego defense mechanis is characterized by a separation of feelings from ideas and events
isolation
Which ego defense mechanis is characterized by an unacceptable internal impulse attributable to an external source?
projection
Which ego defense mechanis is characterized by proclaiming logical reasons for actions actually performed for other reasons, usually to avoid self-blame?
rationalization
Which ego defense mechanis is characterized by a process whereby a warded-off area or feeling is replaced by an (unconsciously derived) emphasis on its opposite?
reaction formation
Which ego defense mechanis is characterized by turning back the maturational clock and going back to earlier modes of dealing with the world?
regression
Which ego defense mechanism is characterized by an involuntary withholding of an idea or feeling from conscious awareness. The basic mechanism underlying all others?
repression
Which ego defense mechanism is characterized by the belief that people are either all good or all bad?
splitting