Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/16

Click to flip

16 Cards in this Set

  • Front
  • Back
Binds ergosterol and forms membrane pores (2)
Amphotericin B
Nystatin
Inhibits ergosterol synthesis
Fluconazoles, "-azoles"
Inhibits DNA syn by conversation to fluorouracil, which competes with uracil
flucytosin
inhibits cell wall syn
caspofungin
inhibits squalene epoxidase
terbinafine
interferes with MT function; disrupts mitosis
griseofulvin.
Clinical use of Ampho B
Systemic mycoses and OI
Intrathecally for fungal meningitis
fever/chills, hypotension, nephrotox, arrhythmias
Amphotericin B
use for nystatin
oral candidiasis;
topical for diaper rash or vaginal candiasis
use for -azoles
systemic mycoses
Fluconazole - cryptococcal meningitis in AIDS and candidal infections
Ketoconazole - Coccidioides, Histoplasma, Blastomyces, Candida; hypercortisolism
gynecomastia, liver dysfunction, fever, chills
-azoles
systemic fungal infections like Candida and cryptoccus; major SE is bone marrow suppression
flucytosine
used for invasive aspergillosis
caspofulgin
used to treat dermatophytoses, especially onchyomycosis
terbinafine
used for oral tx of supf infections; inhibits growth of dermatophytes like tinea, ringworm
griseofulvin
teratogenic, carcinogenic, confusion, H/A, inc warfarin metabolism
griseofulvin