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24 Cards in this Set
- Front
- Back
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-afil
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Erectile dysfunction, ex Sildenafil. MOA: inhibits cGMP-specific phosphodiesterase. NO binds to guanylate cyclase receptors, causing smooth muscle relaxation and vasodilation. Tox: "hot and sweaty," then headache, heartburn, and hypotension.
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-ane
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Inhalational general anesthetic, ex Halothane. Main tox: massive hepatic necrosis, malignant hypertension (tx dantrolene).
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-azepam
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Benzodiazepine, ex Diazepam
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-azine
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Phenothiazine (neuroleptic, antiemetic), ex Chlorpromazine. Haloperidol + -azines = typical antipsychotics.
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-azole
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Antifungal, ex Ketoconazole. MOA inhibits ergosterol synthesis.
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-barbital
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Barbiturate, ex Phenobarbital. MOA increases the duration of GABA-A Cl- channel opening.
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-caine
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Local anesthetic, ex Lidocaine. MOA Na+ channel blocker. Esters have one I, Amides have 2 I's (relevant for allergies).
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-cillin
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Penicillin, ex Methicillin. MOA: beta-lactam drug inhibits transpeptidase, interfering with cell wall synthesis.
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-cycline
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Antibiotic, protein synthesis inhibitor, ex Tetracycline. MOA: binds 30S ribosomal subunit, inhibiting bacterial protein synthesis. Bacteriostatic.
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-etine
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SSRI, ex Fluoxetine
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-ipramine
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TCA, ex Imipramine. MOA: NE/5-HT reuptake inhibitor. Tox: Tri-C's (Convusions, Coma, Cardiotoxicity [arrhythmogenic]) and anticholinergic effects.
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-navir
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Protease inhibitor, ex Saquinavir "navir tease a protease inhibitor".
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-olol
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Beta blocker, ex Propranolol
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-operidol
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Butyrophenone (neuroleptic), ex Haloperidol (typical antipsychotic).
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-oxin
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Cardiac glycoside (inotropic agent), ex Digoxin
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-phylline
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Methylxanthine (similar to caffeine), COPD/asthma, ex Theophylline. MOA: cAMP phosphodiesterase inhibitor -> bronchodilation.
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-pril
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ACE inhibitor, ex Captopril
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-terol
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beta-2 agonist, ex Albuterol
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-tidine
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H2 antagonist, ex Cimetidine
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-triptan
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5-HT1B/1D agonists (migraine), ex Sumatriptan
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-triptyline
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TCA, ex Amitriptyline
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-tropin
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Pituitary hormone, ex Somatotropin
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-zolam
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Benzodiazepine, ex Alprazolam
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-zosin
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Alpha-1 blocker, HTN, anxiety, PTSD, panic disorder, BPH, ex Prazosin
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