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19 Cards in this Set

  • Front
  • Back

What is the main component of opium?

Morphine

What is morphine?

An alkaloid natural product

What are alkaloids?

Nitrogen containing natural products



How are opiates made?

Using petrol in acid base extraction

What is heroin made from?


What is it's systematic name?

Morphine, treated with an acetic anhydride


Diacetyl morphine

What is a prodrug? What are example of prodrugs?

Ones that can cross the blood-brain barrier quickly


E.g. Heroin

What do opioid antagonists do?

Reversibly block the effects of morphine

Can be used to treat overdose as well as addiction


What are clinical uses of ergot alkaloids?

Smooth muscle agonists (aid the delivery of the placenta)

What does SSRI stand for?


What are examples of SSRIs?

Selective Serotonin reuptake inhibitors


Paroxetine (seroxat)


Fluoxetine (prozac)


Serotonin

How are amphetamines make?

Dopamine is made into noradrenaline, which is then made into adrenaline

What types of amphetamines are there?

Amphetamines (speed), methamphetamine (crystal meth) and benzylpiperazine (BZP)

What is MDMA?

3,4-Methylenedioxymethamphetamine


Made by oxidising and reductive amination of safrole

What chemicals can be used in perfumes?

Lauryl aldehyde


Vanillin


Muscle

What are examples of hormone?

Testosterone


Oestrogen


Progesterone

What type of chemical are steroids?

Terpenoids

How do pregnancy tests work?

There is one strip that will react with the chemicals present during pregnancy, one strip that is to test for the chemical and a control strip


Two lines = pregnant, one line = not pregnant, no lines = faulty

What are the steps in making morphine?

Petrol and acid


Chuck the petrol out


Convert acid into alkali


Petrol and alkali


Concentrate petrol and obtain alkali

What are examples of opioid agonists?

Naloxone


Naltrexone


Diprenorphine

What are potent simplified analogues of morphine?

Pethidine


Fentanyl


Methadone