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37 Cards in this Set

  • Front
  • Back
What wavelengths of light can the eye process
400-700 nm
What are the three layers of the eye (outer to inner) and what does each contain?
1. Corneosclereal
Cornea - central
Sclera - dense CT laterally
2. Choroid or uvea - vasculature
3. Retina - rods and cones
What are the functions of the cornea?
1. Protection
2. Structural support
3. Filtration of undesirable wavelengths
4. Focus image on retina
What are the 5 layers of the Cornea and what does each layer contain?
1. Stratified squamous epithelium
2. Bowman's - random collagen fibrils
3. Stroma - layers of kertocytes and collagen fibrils
4. Descemet's membrane - thick basal lamina, dense collagen
5. Simple squamous epithelium - tight junctions
What is myopia?
Nearsightedness, caused by cornea too far from retina
What is hyperopia?
Farsightedness, cornea too close to retina
What is astigmatism?
Aspherical cornea --> light not properly focused on retina
What is Radial Keratotomy?
Incision near center of cornea to correct mild myopia
What is astigmatic keratotmy?
Incision in steepest part of cornea to correct astigmatism
What is photrefractive keratotomy?
Laser removes part of corneal epithelium to correct mild/moderate myopia, hyperopia and astigmatism
What is LASIK?
Laser removes part of stroma to correct hyperopia, astigmatism, and myopia
What is the Limbus and what does it do?
Junction of cornea and Sclera, where Bowman's membrane disappears, vasculature appears

WBC's migrate from here to cornea in inflammation response
What is the conjunctiva?

What are the characteristics of its epithelium?
Lines inner surface of eyelids and eye surface beyond cornea

Continuous with skin epithelium, has goblet cells
What is the function of the lens?
Focus nearby objects on the retina
What are the 4 structural parts of the lens?
1. Capsule - collagen and proteoglycans
2. Cuboidal cells - anterior
3. Flattened cell fibers - extend width of lens, gap junctions
4. Zonules - elastic microfibril, fibrillin support lens
What is Presbyopia?
Loss of lens elasticity
What is cataracts?
Loss of lens transparency
What are the functions of the retina?
1. Photoreception
2. Transmission of images to optic lobe of brain
3. Prevents light backscatter
What are the 9 layers of the retina (post to ant)
1. Rods and codes
2. Outer limiting - tight junctions btwn photoreceptor and Muller glial cells
3. Exteran nuclear layer - cell bodies and nulei of rods and cones
4. External plexiform - photoreceptor axon/interneuron process
5. Internal nuclear - Interneuron cell body
6. Internal plexiform - dendrites of ganglion cells/process of interneurons
7. Ganglion layer - ganglion cell bodies
8. Nerve fiber layer - axons of ganglion
9. Pigmented epithelium - prevent backscatter
What can rods do and not do?
CAN - vision in low light
CANNOT - colors
How does rod concentration change from Fovea?

What is the light sensitive pigment and how does it work?
Increasing concentration as distance increases

Light-sensitive pigment = Rhodopsin --> GPCR bound to vit. A prosthetic group
What do cones do, where are the most abundant, and what is the light-sensitive pigment?
Sense color

Highest conc. in fovea, decrease outward

Iodopsin pigment
What is the fovea centralis?
Visual axis with greatest visual acuity

Highest density of photoreceptors, no vessels
What is the Macula lutea?
Yellow pigment around fovea
Wht is the optic disc?
Where optic nerve joins retina

Since no rods and cones --> blind spot
What are the structures in the choroid/uvea? (5)
Iris
Ciliary body/processes
Vessels
Pigmented region
Outflow tract
What is the job of the iris?
Regulate amount of light that reaches retina
What muscles control pupil size and how are they arranged?
Dilator pupillae = radially from pupil
Constrictor pupillae = circumferentially around pupil
What are the posterior and anterior layers of the iris?
Posterior = layer of blue pigmented cells that blocks light

Anterior = myoepithelial cells with melanin
What is the structure of the ciliary body?
Disk-shaped, hollow core, with lumen of ciliary processes, smooth muscle
What does the outer layer of the ciliary body contain?
Pigmented epithelial cells, continuous with pigmented epithelium of iris
What does the inner layer of the ciliary body contain?
Non-pigmented, produces zonules that anchor basal lamina to lens capsule
What are the functions of the ciliary body?
Accomodate lens, control thickness via zonules
What happens when the ciliary muscle contracts?
Zonule tension decreases, lens thickens, increases index of refraction --> near focus
What do ciliary processes produce?
Aqueous humor into posterior chamber, moves to anterior chamber passively b/c of pressure difference
How does aqueous humor move through the eye?
Ciliary process --> posterior chamber --> anterior chamber --> trabecular meshwork --> canal of Schlemm --> episcleral veins -->general circulation
What is Glaucoma?
Buildup of fluid pressure in eye:
Inflow > Outflow