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12 Cards in this Set

  • Front
  • Back
Experimental Studies
intervention is performed
Clinical Trials
human subjects
Controlled Clinical Trial
human subject with controls
Blind Trial
subject is unaware
Double Blind Trial
researcher and subject are unaware
Advantages and Disadvantages of Double Blind Trial
Advantages: gold standard in medicine providing the strongest evidence. Provides greatest evidence for causation. Subject to least number of biases
Disadvantages: expensive, time-consuming, and may expose patients to harm
Randomized, Controlled trial
subjects are randomized
Cross Over Study
same group of patients is used for experimental and control groups. Experimental and control groups are withdrawn for a wash-out period. Groups then given the alternative treatment
equally distributes the potential effect of bias between groups; methods of random selection done using a random numer table
Treatment allocation
method which determines which treatment a patient will receive (Related to Randomization)
Non-controlled studies
effect of intervention or treatment done on a single group. Possible confounding variables such as: placebo effect, hawthorne effect, natural course of disease, regression toward the mean.
Hawthorne effect
a term coined in reference to a series of productivity studies at the Hawthorne plant of the Western Electric Company in Chicago. The researchers discovered that their presence affected the behavior of the workers being studies; the term now refers to any impact of research on the subject of study