Experimental Methods

Front 1

Selection of method to employ depends upon: (3)

Back 1

1. WHAT measuring
2. HOW measures
3. WHEN & WHY to use the measure

Front 2

Types of Invasive Measures: (3)

Back 2

1. Single/Multi Unit Recording
2. Lesions
3. Genetic Manipulation

Front 3

When to use invasive measures

Back 3

requirement of DIRECT access or change to the brain

Front 4

Types of Lesion Methods: (3)

Back 4

1. Temporary
2. Permanent

Front 5

Types of Genetic Manipulation (3)

Back 5

1. Knock-down: less active gene
2. Knock-in: mutation
3. Knock-out: gene taken out (ability to produce protein removed by alteration/replacement of dummy code)

Front 6

NonInvasive Structural Methods are...what are they? (2)

Back 6

Volumetry Analysis.
1. CT: visualize fractures and leakage, no wh/gr matter diff
2. MRI: exploit NMR and RF.

Front 7

(2) types of MRI

Back 7

1. T1: White matter BRIGHT, view anatomical structures (familliar brain)
2. T2: Grey matter BRIGHT, view tumors, swelling.

Front 8

(2) Types of non Invasive Functional Methods

Back 8

1: Direct: measure n. firing
2. Indirect: measure blood flow

Front 9

(2) Types Direct methods

Back 9

1: EEG- changes in extracellular current, EPSP&IPSP (ERP)
2: MEG- Magnetic field arising from e curent as result of stimulus

Front 10

ERP

Back 10

Event-related Potentials: AVGing of time-locked segments of EEG to stimulus

Front 11

(2) Types of Indirect Methods

Back 11

1. PET- inject of isotopes of glucose or other relevant chemical
2. fMRI- measure areas of blood overcompensation

Front 12

EEG freq oscillations indicate..

Back 12

different processes.