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12 Cards in this Set

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Selection of method to employ depends upon: (3)
1. WHAT measuring
2. HOW measures
3. WHEN & WHY to use the measure
Types of Invasive Measures: (3)
1. Single/Multi Unit Recording
2. Lesions
3. Genetic Manipulation
When to use invasive measures
requirement of DIRECT access or change to the brain
Types of Lesion Methods: (3)
1. Temporary
2. Permanent
Types of Genetic Manipulation (3)
1. Knock-down: less active gene
2. Knock-in: mutation
3. Knock-out: gene taken out (ability to produce protein removed by alteration/replacement of dummy code)
NonInvasive Structural Methods are...what are they? (2)
Volumetry Analysis.
1. CT: visualize fractures and leakage, no wh/gr matter diff
2. MRI: exploit NMR and RF.
(2) types of MRI
1. T1: White matter BRIGHT, view anatomical structures (familliar brain)
2. T2: Grey matter BRIGHT, view tumors, swelling.
(2) Types of non Invasive Functional Methods
1: Direct: measure n. firing
2. Indirect: measure blood flow
(2) Types Direct methods
1: EEG- changes in extracellular current, EPSP&IPSP (ERP)
2: MEG- Magnetic field arising from e curent as result of stimulus
ERP
Event-related Potentials: AVGing of time-locked segments of EEG to stimulus
(2) Types of Indirect Methods
1. PET- inject of isotopes of glucose or other relevant chemical
2. fMRI- measure areas of blood overcompensation
EEG freq oscillations indicate..
different processes.