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35 Cards in this Set
- Front
- Back
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acts at myoneural junction, blocks release of Ach - causes flaccid paralysis
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botulinum tosin - c. botulinum
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treatment against C. botulinum exotoxin
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antitoxin
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treatment against tetanus exotoxin
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toxoid for active immunization. antitoxin for wounds in unimmunized persons
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lecithinase (disrupts cell membrane)
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alpha toxin
Clostridium perfringens treat with antitoxin causes gas gangrene |
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inhibits protein synthesis (ADP ribosylates elongation factor 2)
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diptheria toxin
c. diptherae |
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diptheria toxin has what effect
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kills cells
pseudomembranes in throat myocarditis |
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like diptheria toxin - kills cells - secreted by Pseudomonas aeruginosa
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exotoxin A (inhibits protein synthesis by ADP ribosylating elongation factor 2)
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the alpha toxin secreted by staph aureus has what effect and how
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hemolytic, leukocytic, paralysis of smooth muslce, local necrosis
works by lytic pores in membrane with loss of low molecular weight substances |
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a superantigen which binds to class II MHC protein induces IL-1, IL-2, TNF and results in fever rash and shock
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toxic shock toxin secreted by some strains of s. aureas
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exotoxin secreted by s. aureasu which leads to scalded skin syndrome work how
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exfoliatin is a protease
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works by toxin forming oligimers form in pores
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stretpococcus pyogenss
secreted streptolysin O |
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streptolysin O has what effect
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lysis red blood cells, etc.. (beta hemolysis)
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erythrogenic toxin causes what and is secreted by what organism
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streptococcus pyogens and causes scarlet fever by acting as a superantigen
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pyrogenic exotoxin A causes
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streptococcal toxic shock syndrome - works as a superantigen
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cuases massive diarrhea by activation of adenylate cyclase
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cholera toxin
acts by ADP ribosylation |
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heat labile (LT) enterotoxin causes diarrhear by activation of adenylate cyclase, is secreted by E. coli and is identical to what other toxin
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cholera toxin
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heat stable enterotoxin (ST) secreted by E. coli works by
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acts on adenylate cyclase
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cytotoxin (verotoxin) is secreted by and causes what
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secreted by E. coli and causes bloody diarrhea (hemorrhagic colitis) as well as kidney damage
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cytotoxin (Shiga toxin) kills cells by
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inhibiting protein synthesis (inactivating the 60S ribosome)
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works by activating adenylate cyclase and causes cough
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pertussis toxin which causes whooping cough
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edema factor, lethal factor, and protective antigen are all secreted by
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bacillus anthracis
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toxin that causes dysentary
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shigella
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live attenuated (BCG) vaccine protects against
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tb
not used in U.S. |
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vaccine for whooping cough
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purified protein (part of DTap vaccine)
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organism that cuases typhoid
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salmonella typhi
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vaccine for thyphoid
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killed bacteria or live attenuated
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vaccine for meningitis caused by neisseria meningitidis
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capsular polysaccharide A and C (two of the most common antigenic types) (Y and W also available)
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vaccine for meningitis caused by haemophilus influenzae
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capsular polysaccharide type b conjugated to carrier protein (Hib)
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three classes of spore fromers
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1. all members of clostridim
2. all members of Bacillus 3. Coxiella burnetti (forms a stable extracellular stage that is termed "spore-like" but sometimes simply called spore |
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what kind of bacteria are clostridium
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gram postive
obligate anaerobic rods |
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what kind of bacteria are bacillus
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gram positive
aerobic rods |
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name the 5 obligate anaerobes in this course
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1. Clostridia
2. Bacteroides 3. Fusobacterium 4. Actinomyces 5. Peptostretococcus |
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3 obligate intracellular bacteria
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1. all chlamydia
2. all rickettsia 3. mycobacterium leprae |
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7 facultative inracellular bacteria
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1. mycobacterium
2. salmonella typhi 3. listeria monocytogens 4. Brucella species (w/mo) 5 Legionella pneumophilia 6. Yersinia pestis (wi/mo) 7. Francisella tularensis (wi/mo) |
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predominately intracellular fungi
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histoplasma capsulatum
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