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35 Cards in this Set

  • Front
  • Back
acts at myoneural junction, blocks release of Ach - causes flaccid paralysis
botulinum tosin - c. botulinum
treatment against C. botulinum exotoxin
treatment against tetanus exotoxin
toxoid for active immunization. antitoxin for wounds in unimmunized persons
lecithinase (disrupts cell membrane)
alpha toxin
Clostridium perfringens
treat with antitoxin
causes gas gangrene
inhibits protein synthesis (ADP ribosylates elongation factor 2)
diptheria toxin
c. diptherae
diptheria toxin has what effect
kills cells
pseudomembranes in throat
like diptheria toxin - kills cells - secreted by Pseudomonas aeruginosa
exotoxin A (inhibits protein synthesis by ADP ribosylating elongation factor 2)
the alpha toxin secreted by staph aureus has what effect and how
hemolytic, leukocytic, paralysis of smooth muslce, local necrosis

works by lytic pores in membrane with loss of low molecular weight substances
a superantigen which binds to class II MHC protein induces IL-1, IL-2, TNF and results in fever rash and shock
toxic shock toxin secreted by some strains of s. aureas
exotoxin secreted by s. aureasu which leads to scalded skin syndrome work how
exfoliatin is a protease
works by toxin forming oligimers form in pores
stretpococcus pyogenss
secreted streptolysin O
streptolysin O has what effect
lysis red blood cells, etc.. (beta hemolysis)
erythrogenic toxin causes what and is secreted by what organism
streptococcus pyogens and causes scarlet fever by acting as a superantigen
pyrogenic exotoxin A causes
streptococcal toxic shock syndrome - works as a superantigen
cuases massive diarrhea by activation of adenylate cyclase
cholera toxin
acts by ADP ribosylation
heat labile (LT) enterotoxin causes diarrhear by activation of adenylate cyclase, is secreted by E. coli and is identical to what other toxin
cholera toxin
heat stable enterotoxin (ST) secreted by E. coli works by
acts on adenylate cyclase
cytotoxin (verotoxin) is secreted by and causes what
secreted by E. coli and causes bloody diarrhea (hemorrhagic colitis) as well as kidney damage
cytotoxin (Shiga toxin) kills cells by
inhibiting protein synthesis (inactivating the 60S ribosome)
works by activating adenylate cyclase and causes cough
pertussis toxin which causes whooping cough
edema factor, lethal factor, and protective antigen are all secreted by
bacillus anthracis
toxin that causes dysentary
live attenuated (BCG) vaccine protects against
not used in U.S.
vaccine for whooping cough
purified protein (part of DTap vaccine)
organism that cuases typhoid
salmonella typhi
vaccine for thyphoid
killed bacteria or live attenuated
vaccine for meningitis caused by neisseria meningitidis
capsular polysaccharide A and C (two of the most common antigenic types) (Y and W also available)
vaccine for meningitis caused by haemophilus influenzae
capsular polysaccharide type b conjugated to carrier protein (Hib)
three classes of spore fromers
1. all members of clostridim
2. all members of Bacillus
3. Coxiella burnetti (forms a stable extracellular stage that is termed "spore-like" but sometimes simply called spore
what kind of bacteria are clostridium
gram postive
obligate anaerobic
what kind of bacteria are bacillus
gram positive
name the 5 obligate anaerobes in this course
1. Clostridia
2. Bacteroides
3. Fusobacterium
4. Actinomyces
5. Peptostretococcus
3 obligate intracellular bacteria
1. all chlamydia
2. all rickettsia
3. mycobacterium leprae
7 facultative inracellular bacteria
1. mycobacterium
2. salmonella typhi
3. listeria monocytogens
4. Brucella species (w/mo)
5 Legionella pneumophilia
6. Yersinia pestis (wi/mo)
7. Francisella tularensis (wi/mo)
predominately intracellular fungi
histoplasma capsulatum