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75 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What does the ASPCA stand for?
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American Society for the prevention of Cruelty to Animals
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What does the AALAS stand for?
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American Association for Lab Animal Science
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What does the ILAR stand for?
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Institute of Labratory Animal Research
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What does the AAALAC stand for?
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American Association for Accredidation of Labratory Animal Care
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What does the AWA stand for?
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Animal Welfare Act
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Wat is the ASPCA do?
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Promote humane prinicples and prevent cruelty to animals
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Wat is the AALAS do?
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Deals with production, care and study of Lab Animals
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Wat is the ILAR do?
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Make scientific data available to the scientific community so research is not repeated
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Wat is the AAALAC do?
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Promotes voluntary accredidation for humane tx of animals in research science
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Wat is the AWA do?
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Make unannounced visits to verify regulations are being carried out
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What is an Animal "Model"
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An animal chosen for research because of its similarities to the species that the research is being applied to
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What is the criteria for selecting an animal model?
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1)Similar characteristics
2)Size 3)Productivity 4)Longevity |
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What are the three main genetic categories used in biomedical research
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1)Outbred Stock
2)Inbred Strains 3)FI Hybrids |
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1)What is Outbred Stock?
2)Is is strong or weak? |
1) Produced in large colonies
Mating very random Litters very unrelated 2) Strong |
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1)What is Inbred Stock?
2)Is is strong or weak? |
1)Brother/Sister
Usually 20+ generations Very homogeneous (similar) Used to select specific trait or characteristics 2) Weak |
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1)What is FI Hybrids Stock?
2)Is is strong or weak? |
1)result of 2 different inbred strains
2)Offsprings stronger than parents |
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What are the Ecologic Animal Types in research?
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Axenic
Gnotobiotic (note-o-biotics) Specific Pathogen-Free Conventional |
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What is the microbial purity of Axenic animals?
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Sterile
Free of all detectable microflora (Most expensive - housing must be sterile at ALL times) |
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What is the microbial purity of Gnotobiotic animals?
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Known type/s of microflora
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What is the microbial purity of Specific Pathogen-Free Animals?
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"SPF's" free of specific pathogens
(Most commonly used) |
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What is the microbial purity of Conventional animals?
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Undefined microflora
(Collected from anywhere) |
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What are the housing factors for lab animals?
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1) Temp control - 64-79f
2) Humidty control - 30-70% 3) Light Control - 12-14 hr cycle 4) Air control - 10-15 changes per day |
There are 4
There IS regulations on this one!!! |
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What is the average weight of a rat?
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300-400 grams
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What is the average weight of a mouse?
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25-40 grams
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What is the average lifespan of a rat?
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2 1/2 - 3 years
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What is the average lifespan of a mouse?
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1 1/2 - 3 years
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What is the average puberty age of a rat?
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6-8 weeks
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What is the average puberty age of a mouse?
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6-8 weeks
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What is the average gestation period of a rat?
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3 weeks
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What is the average gestation period of a mouse?
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19-21 days
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What are is the scientific name for a rat?
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Rattus Norvegicus
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What are is the scientific name for a mouse?
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Mus Musculus
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Why are mice most commonly used in research?
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1) Short life span
2) Short gestation 3) Large Litters 4) Inexpensive 5) Easy to maintain |
There are 5 of them listed
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What are mice used for?
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1) Toxicity
2) Food 3) Pets |
There are 3 of them on this one
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What are rats used for?
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1) Research
2) Pets 3) Food |
There are 3 of them listed
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What is important to know about the teeth of mice and rats?
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They are open rooted
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What does open rooted mean?
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They continue to grow
Something is needed to grind them down or they need to be cut |
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How should you house mice?
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1)Small groups
2)Seperate males & females 3)Bedding of wood chips 4)Hiding Spots |
There are 4
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How should you house rats?
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1)Large cage
2)Small spacing between bars |
There are 2
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Rats:
What do they eat? How much do they eat? How much do they drink? |
Lab blocks
Eat: Approx 20 grams/day Drink: Approx 1-2 tsp/day |
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Mice:
What do they eat? How much do they eat? How much do they drink? |
Lab blocks
Eat: 3-5 grams/day Drink: Approx 5 mls/day (1tsp) |
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What is the behavior pattern of Mice?
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Males = Territorial
Coprophagic Nocturnal Great nest bilders Infrequently bite Quite |
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What is the behavior pattern of Rats?
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Usually quite
Usually friendly Develop personalities Trainable Nocturnal (more than mice) Seldom bite Males: Rarely fight Great escape artists |
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What are the identification methods of Mice & Rats?
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1)Ear notching
2)Ear tagging 3)Microchip 4)Fur dying 5)Ink tail markings |
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What is the Whitten effect?
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Females housed together
Male introduced Estrus cycle will be syncronized |
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What is the Bruce effect?
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Female mouse will abort if a strange male is introduced within 4 days of breeding
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Does the Whitten effect occur in Mice, Rats, or Both?
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Both
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Does the Bruce effect occur in Mice, Rats, or Both?
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Mice
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How do you sex a mouse or rat?
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Males: longer distance between anus and urogenital opening
You may see the testicles. |
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Why can it be hard to see testicles on a male?
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They have open ingunial canals that they testicles can retract into
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What does MRM stand for?
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Murine Respiratory Mycoplasmosis
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What is MRM?
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Murine Respiratory Mycoplasmosis
Cronic disease Caused by Bacteria - Mycolplasma Pulmonis |
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What are the signs of MRM?
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Murine Respiratory Mycoplasmosis
Dyspnea Rattling sneezing snuffy sounds Later: Weight loss Head tilt Pneumonia Occ. increase of Red tears |
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What is Sendai irus
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Causes pheumonia
May become susesptible to secondary infections |
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1)What is Obesity?
2)Who is more prone to it? 3)Why? |
1)Overweight
2)Pet Rats 3)Too many treats Poor diet |
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What are two Ocular conditions?
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Periocular Porphyrin Staining
Retinal Atrophy |
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Periocular Porphyrin Staining
1)What is it caused by? 2)What happens? |
1)Non-specific
Stress Disease 2)Red tears secreted from Harderian Gland |
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Retinal Atrophy
1)What is it? 2)What is it caused by? 3)Sign? 4)Who is most prone to it? |
1)Retinal detachment
2)Exaberated by lighting intesity 3)Head tilt 4)Older albino rats |
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What type of tumors do Rats usually have?
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Benign
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Where do female rats usually get tumors?
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Mammary Tumors
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Urinary Bladder Worms:
1)What is the scientific name? 2)Do they matter? 3)What do they look like? |
1)Trichosomoides Crassicauda
2)No - just a finding 3)Chains of dark brown eggs |
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Ring Tail:
1)What is it? 2)What causes it? 3)Sign? |
1)One or more constrictions of the tail
2)Low humidity (should be kept at greater than 50% 3)Constriction becomes necrotic and falls off after swelling |
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Malocclusion:
1)What is it? 2)What is a sign? |
1)Overgrowth of incisors
2)Anexeria |
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Rat Bite Fever:
1)What is it? 2)What does it cause? |
1)Bacterial infection
(Strep) 2)Septasemia & arthritis in people |
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Hantavirus:
1)Who is the primary host? 2)Host signs? 3)How is it shed? 4)Causes? |
1)Wild rodents
2)No clinical signs 3)urine Saliva Feces 4)Hemoragic fever with Renal symptoms |
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Bite Wounds:
1)Cause? 2)Area it affects? |
1)fighting of dominant males
2)Genital & tail |
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Barbering:
1)What is it? 2)What occurs? |
1)Fur Chewing
2)Dominant male/females do to other housemates |
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External Parasites:
1)What are they? 2)What are the signs? |
1)Lice & Mites
2)Itching Hair loss Self mutilation |
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Tyzzer's Disease:
1)What is it caused by? 2)What are the symptoms 3)Who does it affect? |
1)Bacteria: Clostridium piliforme
2)Diarrhea Dehydration Hunched back 3)Rodents & other species |
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EPIM:
1)What does it stand for? 2)What is it? 3)Who does it affect? 4)What are the symptoms? |
1)Epozotic Diarrhea in Mice
2)Rotavirus 3)Mice less than 2 wks old 4)Soft yellow stool Dried feces around rectum Stunted growth |
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What are the 6 ways to collect blood from rats?
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Retroorbital sinus
Jugular Vein Cephalic Vein Tail vessel Toe nial clip Cardiac puncture |
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What are the 4 ways to collect blood from mice?
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Retroorbital sinus
Tail vessels Toe nail clip Cardiac puncture |
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What are 5 ways to give meds?
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SQ - Scruff or abdomen
IM - Quadriceps IV - Lateral tail vein (mouse) Jugular (Rat) IP - Intaperitoneal PO - Mouth |
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What are ways to euthanize mice & rats?
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Carbon dioxide
Barbiturate overdose Cervical dislocation (mice only) Decapitation Ether Exsanguinate |
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How do you restrain a mouse?
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Hold upright
Extend head & neck Keep nose, head & neck aligned Do not allow rodent to tip back |
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