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20 Cards in this Set

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  • Back
Framingham Heart Study
Longitudinal study where a random sample of participants underwent physical examinations every 2 years to identify risk factors for heart disease.
Strong positive correlation
"correlation" does not = "causation"
Tecumseh Community Health Studies
Examined an entire community in Michigan for biological, physical, and social environment to reveal how some people maintain good health while others are more susceptible to disease.
30 new cases of diabetes in a community per year, 1000 per year?
Incidence=3 per 100 persons per year.
Railroad study
RR of unfit at both exams > RR of unfit at 1st and 2nd > RR of fit at both exams
Railroad study death rates:
(Highest death rate) clerks > switchmen> section men (lowest death rate)
Elevated systolic & diastolic BP are due in part to:
Increased cardiac output and total peripheral resistance.
Embolic Stroke
Due to altered electrical conductivity of the heart as a result of a recent MI or infection
Lacunar Stroke
Due to stenosis and reduced perfusion of carotid arteries of the brain.
Harvard Alumni Study
Men who expended 2000 kcal/wk or more in exercise gained 1.25 years of life when compared to sedentary men.
Primary modifiable risk factor for stroke:
Hypertension
Framingham Heart Study
Sedentary men=higher relative risk
Is there a dose response relationship between physical activity and coronary heart disease?
Yes.
Obesity combined with type 2 diabetes and hypertension reduces life expectancy by how much?
1 year.
Lipotoxicity
Depositing of excess lipid in organs that may contribute to insulin resistance in obesity.
What percent with diabetes mellitus develops blindness?
2%
What percent of U.S. healthcare budget goes to obesity?
12%
Prevalence of high LDL cholesterol in U.S.?
40-50%
Metforamin
Diabetes, for hyperlipidemia
Post exercise:
Increase in HDL-cholesterol and reduction in TG & LDL cholesterol