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88 Cards in this Set

  • Front
  • Back
Nonspecific lines o defense from pathogens that include barriers, protective cells and chemicals
Innate immunity
specific lines of defense involving cells of the immune system that target specific markers on pathogens
Adaptive Immunity
Skins is composed of two layers:
Epidermis
and dermis
Dermis:
lies under epidermis and contains hair follicles, glands and nerve endings
epidermis
Tightly packed cells
Epidermis contains ____
cells
Langerhans cells or epidermic dendritic cells that phagocytize pathogens nonspecifically
Dermis has:
Collegen to make skin pliable and tough to prevent cuts and contains sweat which contains sals
Lysozomes
Destroy cell wall of bacteria
___ glands secrete sebum
Sebaceous
Mucous membranes are composed of
epithelium (outer layer of cells) and connective tissue (provides blood)
_____ cells produce mucus which traps pathogens and propelled out of body by ciliated columnar cells
Goblet Cells
Another name for antimicrobial peptides
Defensins
Cystic Fibrosis kills ____
Columnar Cells
The normal flora can change Ph and compete for nutrients against possible pathogenic organisms
Microbial Antagonism
Axenic
Microbe Free
Sweat Glands give us
Salt
Ferrin is latin for
Iron
White Blood cells that defend body against invaders
Leukocytes
secrete tears which contain lysozyme to destroy and wash away bacteria
Lacrimal Apparatus
The Body's Second Line of Defense is
Cells of the Blood
____ is made up of mostly water and contains electrolytes (ions) dissolved gases and nutrients and proteins (platelets)
Plasma
Serum is Plasma without what
clotting factors
Red blood cells are
Erthrocytes
White blood cells are
leukocytes
platelets
Clot Blood
Platelets are formed from
megakaryocytes
The body traps iron using ____
transferrin
Staphylococcus Aureus secretes what
siderophores
siderophores do what
steal iron from body
hemolysin bursts red blood cells and releases what
their hemoglobin
The body traps iron using
transferrin
Staphylococcus aureus secretes
siderophores
hemolysin does what
bursts red blood cells
2 types of leukocytes are
granculocytes and agranulocytes
granulocytes have large granules and includes
neutrophils, eosinophils, and basophils
basophils release
inflammatory chemicals
easinophils attack
parasitic worms and cause allergic reactions
agranulocytes include
lymphocytes and monocytes
monocytes are
immature macrophages
_____ macrophage wander thoughout the body
wandering macrophage
____ macrophage
are in the lungs
_____
are in the central nervous system
_____ cellls
are in the liver
_____ cells
are found in the epidermis
MAC
membrane attach Complex
What involves the use of pseudopodia to crawl towards pathogens
chemotaxis
phagocytes attach to pathogens by binding to glycoproteins
adherence
phagocytes are attracted to sides of infection by
chemokines
The coating of organisms which complement proteins for easier phagocytis
opsonization
After adherence, the pseudopodia envelope the organism and internalize it as a vessible called a
phagosome
lysosomes fuse with the phagosome forming a
phagolysomes and they digest it
the remnants are exocytosed or expelled
elimination
Serum proteins which acts as opsonins and chemokines triggering inflammation and fever
complement system
lymphocites are nonspecific leukocytes that secrete toxins on virally infected cells and tumors
natural killer cells
pathyway - complement is activated when they attach to antibodies attached to the surface of pathogens
classical
_____ pathway begins with cleavage of the C3 Complement protein which leads to the cleaving of other complement proteins leading to a cascading effect
Alternative
protein molecules released by host cells to nonspecifically inhibit the spread of viral infections
interferons
three classes of interferons
alpha, beta and gamma
___ Inflammation develops quickly and ends quickly
acute
___ inflammation developes slowly and lasts a long time
chronic
____ is the sticking of phagocytes to walls of blood vessels before diapedesis
margination
____ and leukotrienes cause vessels to leak fluid casing edema
prostaglandins
increased temps are triggered by
pyrogens
a pyrogen released by phagocytes that have phagocytized bacteria causes hypothalamus to increase thermostat setting
interleukin-1
Study of the body's immunity cells and chemicals
immunologists
three dimensional shapes of regions that the immute system recognizes as foreign
epitopes
____ antigens are outside of cell
exogenous
___ antigen are inside cell
endogenous
____ self antigen found in body's normal cell
autoantigens
Molecules that trigger a specific immune response
antigen
considered the third line defense is a smart system with memory capabilities
adaptive immunity
composed of lymphatic vessesls, cells, tissues, organs
lymphatic system
form a one way system conductin lymph, a colorless, watery substance much like plasma
lymphatic vessels
The smallest leukocytes (white blood cells)
lymphocytes
lymphatic organs include
spleen, tonsils, mucosa-associated lymphatic tissue (MALT)
B Lymphocytes originate in
the red marrow of bone and mature there as well
B Cells have surface antibodies and are found primarily in the spleen, nodes and MALT called
plasma cells when actively fighting exogenous antigens
another name for antibodies
immunoglobulin and are soluble antigen binding proteins secreted by B Cells
This is a part of what immune response
Humoral
ABS means
Antigen Binding Sites
particular antigenic determinant
epitope
A toxin or block bacterial and viral attachment to cells by binding to a critical portion so it can no longer be virulent
ADCC
a way of enhancing phagocytosis by covering antigen with antibody
opsonization
some antibodies are able to catalyze the production of hydrogen peroxide
Oxidation
with multiple binding sites, antibodies can attach to more than one microbe and bind several tgether hindering virulence
agglutination
____ consititutes 12% of serum antibody and comes as a monomer that circulates in blood
IGA
Secretory Iga found in secretions like tears and milk
Dimmer
3rd most common AB in initial states of an immune response
IgM