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17 Cards in this Set

  • Front
  • Back
Cell Cell communication in:
-Multicellular organisms
-unicellular organisms(bacteria,yeast)
Special about Cell Cell communication in Yeast
mating factor detection
-cells stop cell division and prepare for DNA exchange
Signaling Cells
Produce signal molecules.
Target cells
Detect the signal molecule and respond to the signal
SIgnal transduction
conversion of extracelular signal to intracellular signal
Signals can be sent over..
Over a long or short range via:
-Paracrine, endocrine, neural, contact dependent.
Contact dependent signaling
controls nerve cell production in drosophila fruit fly
Contains:
membrane bound inhibitory signal protein(Delta) and receptor protein(notch)
Cells respond to...
A limited set of signals, depending on history and current state.
What is special about acetocholine?
Various responses are induced by it
Response to signal molecules
-receptor
-intracellular signaling molecules
-effector proteins
---these are all different consequences!
A typical cell...
Has many types of receptors
-no signal = death(apoptosis)
Cells are sensistive
to many different extracellular signals
A small number of
signal molecules can work in combination, exerting subtle and complex control.
Stimuli can cause cell to...
Survive, grow and divide, differentiate.
Speed of cell response
Fast or slow
-Fast: Altered protein function (pre-existing)
Slow: Requires Protein synthesis
Two classes of extracellular signal molecules
-molecules that cannot penetrate the plasma membrane(large/ charged)..cell surface receptor.
-Molecules can penetrate the membrane(small/hydrophobic)..intracellular receptor.
types of signaling molecules
(7)
-protein, peptide, Amino acid, nucelotide,steroid, FA derivative,dissolved gasses