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13 Cards in this Set

  • Front
  • Back
*... *

-Incomplete descent of testis
-Found in 1% of 1 yo boys
-Usually is an isolated anomaly
-In most patients the undescended testis is palpable in the ...
-Infertility
-Greater risk of developing ...
Cryptorchidism
inguinal canal
testicular cancer
*Hydrocele*

-Collection of serous fluid that results from a defect or irritation in the ... of the scrotum
-In a communicating (congenital) hydrocele, a patent processus vaginalis permits flow of peritoneal fluid into the scrotum. ... inguinal hernias are associated with this type of hydrocele.
-In a noncommunicating hydrocele, a patent processus vaginalis is present, but no ... with the peritoneal cavity occurs
-Adult hydroceles are usually late-onset (secondary). Late-onset hydroceles may present ... from local injury, infections, and radiotherapy; they may present ... from gradual fluid accumulation
tunica vaginalis
Indirect
communication
acutely
chronically
*... *

-An abnormal enlargement of the veins in the scrotum draining the testicle
-Feels like a “bag of worms”
-May lead to ... due to adverse effects of increased temperature on sperm
Varicocele
infertility
*.../... *

-Usually related to cystitis, prostatitis, or urethritis that spreads through vas deferens or lymphatics
-Acute disease: epididymis enlarged, covered with fibrin, may contain pus and rupture
-Children: usually gram ... rods, congenital genitourinary abnormality
-Sexually active men age 35 or less: ..., ...
-Men age 35+: ..., Pseudomonas, other urinary tract infection organisms
Epididymitis/Orchitis
negative
Chlamydia trachomatis, Neisseria gonorrhoeae
E. coli
*... *

-Twisting of spermatic cord -> impaired of blood flow
-Urologic emergency
-Can result in testicular ...
-Usually occurs in ... year of life, also towards ... due to trauma or violent movement
- Associated with incomplete testicular descent, absent scrotal ligaments, absent gubernaculum testis or testicular atrophy causing testis to be abnormally mobile
-Torsion must last at least 6-24 hours to cause an ...
Torsion
infarction
first
puberty
infarct
*Testicular Cancer Presentation*

-... mass with enlarged testicle
-Feeling of ... in testicle or groin
-... accumulation in scrotum
Painless
heaviness
Fluid
*Testcular Germ Cell Tumors*

1) ...

2) ...
-Choriocarcinoma
-Yolk sac tumor
-Embryonal carcinoma
-Teratoma
Seminoma
Non-seminomatous germ cell tumors
*Seminoma*

-Most common germ cell tumor (~50% of cases)
-... is ovarian counterpart
-Arise from ...
-~40% have increased ... levels and ~15% have elevated HCG levels – typically not as high levels as choriocarcinoma
-... prognosis
-Gross: bulky, homogenous gray-white with lobulated and bulging cut surface, usually well demarcated
Dysgerminoma
seminiferous tubules
placental alkaline phosphatase (PLAP)
Excellent
*Choriocarcinoma*

-0.3% to 1% of germ cell tumors are pure choriocarcinoma, but ... tumors are more common
-Identical tumors arise in placenta, ovary, mediastinum or abdomen
-Increased serum ...**
-... behavior
-Hematogenous spread early to lungs, liver and brain
-Pure choriocarcinoma has ... prognosis
mixed
hCG
Aggressive
poor
*Yolk sac tumor*

-Mimics embryonal yolk sac tissue
-Most common testicular tumor for children under age ...
-Often ...
-... prognosis
-Adults: usually part of a ... tumor, has prognosis of embryonal carcinoma
-Most patients (>95%) with tumors containing yolk sac elements have elevated serum ...**
4
pure
Good
mixed
AFP
*Testicular CA Tumor Markers*

Important for ... and follow-up.

...
-Normally made by placental cells
-greatly increased in choriocarcinoma; sometimes increased in seminoma or embryonal carcinoma

...
-Normally made by fetal yolk sac and other cells
-increased in yolk sac tumors and embryonal carcinoma
staging
Human chorionic gonadotropin (hCG)
Alpha-fetoprotein (AFP)
*... *

-Extremely common
-Increases with age, affects ~70% of men age 60
-Symptoms of urinary ...
-... play a key in the development of BPH
-Proliferation of ... and ...
-Tumor marker: elevated prostate specific antigen (PSA) is often seen but usually PSA does not exceed 10 mg/ml
-if PSA is >10, think ...
Benign Prostatic Hyperplasia
obstruction
Androgens
glands and stroma
cancer
Prostate Cancer

-300,000 cases/year in US (#1 after skin cancer)
-41,000 deaths/year (#2 after lung cancer)
-20% of American men are diagnosed with prostate cancer during their lifetimes
-3% die of prostate cancer
-... have the highest incidence and mortality
-Often ...
-Detected by ... test and digital rectal exam
African-Americans
asymptomatic
PSA