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14 Cards in this Set
- Front
- Back
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Hypersecretion of aldosterone is also known as ... syndrome.
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Conn’s
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True or False: regulation of aldosterone is independent of ACTH
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true
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look at slide 26
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ok
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In ..., a pituitary tumor releases excessive amts of ACTH, which results in increased cortisol secretion by the adrenal glands
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cushing’s disease
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... = high aldosterone, high renin
... = low aldosterone, low renin ... = high aldosterone, low renin slide 40 |
secondary hyperaldosteronism
apparent mineralocorticoid excess primary hyperaldosteronism |
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... - a genetic disorder characterized by a deficiency in the hormones cortisol and aldosterone and an over-production of the hormone androgen, which is present at birth and affects sexual development.
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Congenital adrenal hyperplasia (CAH)
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hirsutism, acne, anovulation and infertility are a ... presentation
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hyperandrogenism
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A patient presents and is diagnosed w/ neisseria meningitis and has an acute adrenal insufficiency. What should you expect?
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Waterhouse-friderichsen syndrome
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Catecholamine secreting tumor that arise from chromaffin cells of the adrenal Medulla and the sympathetic Ganglia are referred to as ...
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Pheochromocytomas
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What should you do if you see any of these?
-Paraganglioma, bilateral adrenal pheochromocytoma, unilateral adrenal pheo and a family history of pheos or paraganglioma, unilateral adrenal pheo onset at young age |
genetic testing
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Episodic symptoms of pheochromocytomas:
Occurs in ..., or paroxysms, that can be extremely variable in presentation (forceful heartbeat, pallor, tremor, headache, diaphoresis). hyperadrenergic |
spells
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in patients who have resistant hypertension and a familial syndrome that predisposes to catecholamine-secreting tumors (eg. MEN2, NF1, VHL), you should suspect a ...
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pheochromocytoma
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Lab findings for a pheo:
diagnosis must be confirmed biochemically -increased concentrations of fractionated catecholamines and fractionated metanephrines in the urine or plasma ...: reliable (unless it’s a child) -case-finding methods for identifying catecholamine-secreting tumors is measurement of metanephrines and catecholamines (sensitivity, 98%; specificity, 98%). |
24-hour urine collection
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What should be avoided w/ pheochromocytoma in pregnancy?
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spontaneous labor and delivery
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