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23 Cards in this Set
- Front
- Back
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Major mechanism of Pseudomonas resistance
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Efflux pumps
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Which antibiotics do Gram positive beta Lactamase producing organisms hydrolyze?
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Penicillins
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Which antibiotics do Gram negative betalactamase producing organisms hydrolyze?
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Penicillins and cephalosporins
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Which organisms produce AmpC betalactamase?
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Enterobacter and pseudomonas
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Which organisms produce ESBL betalactamase?
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E. coli and Klebsiella
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Which organisms produce carbapenemase?
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Klebsiella
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Which betalactamase is NOT inhibited by betalactamase inhibitors?
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AmpC
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How do AMEs provide inactivate aminoglycosides?
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Add functional groups to the molecule (acetylation and adenylation for gentamicin and tobramycin, phosphorylation for amikacin)
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How does MRSA gain resistance against beta-lactams ?
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New gene cassette for altered PBPs
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How does penicillin resistant strep pneumo gain resistance against beta-lactams?
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Mosaic PBP
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Normal skin flora
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CNS staph
Streptococci Diphtheroids |
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Normal mouth/oral flora
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Streptococci
Neisseria Hemophilus Bacteroides |
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Normal GU tract flora
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Enterobacteriaceae
Lactobacillus Staphylococci |
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Normal GI tract flora
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Enterobacteriaceae
Bacteroides sp. Clostridium sp. Streptococci (anaerobics) Enterococci |
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Difference between Staph epidermidis and Staph aureus
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Staph epidermidis is coagulase negative and Staph aureus is coagulase positive
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Difference between Strep and Staph
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Staph is catalase positive, Strep is catalase negative
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Strep pneumo hemolytic properties
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Alpha hemolytic
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Strep pyogenes hemolytic properties
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Beta hemolytic, group A
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Enterococcus hemolytic properties
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Gamma hemolytic, salt tolerant
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List 2 Gram positive bacilli
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Lactobacillus
Diphtheroids (corynebacterium) |
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List 2 Gram negative diplococci
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Moraxella
Neiserria |
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Empiric therapy for children with osteomyelitis
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Oxacillin/nafcillin
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Empiric therapy for IVDU with osteomyelitis
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Antipseudomonal betalactam and vancomycin
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