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19 Cards in this Set
- Front
- Back
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What are the antiplatelet meds? |
aspirin clopidigrel (plavix) Ticlopidine (Ticlid) |
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What are indications for antiplatelet meds? |
-ischemic stroke -angina -coronary stenting -acute MI -prevention of MI (81mg aspirin) |
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-What does heparin do? |
prevents thrombin from converting fibrinogen to fibrin - prevents new thrombus formation |
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What are the LMWHs? |
-Enoxaprin (Lovenox) -Dalteparin (Fragmin) |
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What is heparin used for? |
evolving stroke -massive DVT & PE -Acute MI |
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What is heparin's antidote? |
protamine sulfate |
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What labs do you need to check with heparin? |
aPTT 60-80seconds -check q 4-6 hours |
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What is a major side effect of heparin? |
thrombocytopenia- antibodies formed that attack heparin platelet complexes leading to thrombocytopenia |
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How does warfarin work? |
suppresses vitamin K clotting factors |
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What does warfarin treat? |
long term use prevents VTE, PE, prevents thrombosis in pts with prosthetic heart valves and afib |
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What labs do you watch with warfarin? |
PT-INR, INR is 2-3 |
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What is the antidote to warfarin? |
vitamin K and fresh forzen plasma |
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What are the new oral direct thrombin inhibitors? |
dabigatran (Pradaxa) -Apixaban (Eliquis) |
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What are the uses of the oral direct thrombin inhibitors? |
dabigatran (pradaxa) -Apixaban (Eliquis) treats afib and prevents DVTs |
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How should oral direct thrombin inhibitors be taken? |
with food or PPI to prevent dyspepsia |
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What are the factor Xa inhibitors? |
Rivaroxaban (xarelto) |
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What are the thrombolytic (fibrinolytic) meds? |
alteplase (tPA) tissue plasminogen activator) -tenecteplase -reteplase |
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What are thrombolytic meds used to treat? |
acute MI, pulmonary embolism, ischemic stroke |
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What are CI for thrombolytic drugs? |
if anticoagulated (INR >2), internally bleeding, or BP > 180/110 (risk of intracranial hemorrhage) |
