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32 Cards in this Set

  • Front
  • Back
Genetic Linkage
the proximity of two or more markers on the chromosome the closer together they are the lower the probability they will be seperated during recombination the parternal type progeny exceeds that of recombinant progeney
Recombination
The process by which offsrping derive a combination of genes different from that of the parent the generation of new allele combinations in higher organisms this can occur by crossing over
Syntenic
relationships between two or more loci found to be located on the same chromosome
Chi square test
is what geneticists use in order to account for the fact that the size of an experimental population is an impoortant component of statistical significance
Chiasmata
they represents regions in which non sister chromatids of nonsister chromatids of homologous chromosomes cross over often sites of chromosome breakage and exchange resulting in some genetic recombination
Genetic markers
genes that serve as points of reference in determining whether particular progeney was a result of recombination
Terminalization
The shifting of the chiasmata from their original position at the centromere toward the chromosome end or telomere this happens during anaphase
Recombination frequency
the frequency in occurence of recombinatn progeney can be used as an indication of the physical distance seperating any two genes on a chromosome
Chromosomal interference
this may exist in order to the phenomeonon of crossovers not occuring independly to ensure that every pair of homologous chromosomes undergoes at least one crossover event
Ascus
Ascospore
The four haploid products of meoisis that are housed in a sac the hapoid cells are called ascospores and they can germinate and survive as viable haploid individuals that grow and perpetuate themselves by mitosis
Tetrad
there are two definition of a tetrad one is the four products of a sigle meiosis held together in a sac the other definistion was earlier when a tetrad was four homologous chromatids two in each chromosome of a bivalent synapsed during prophase and metaphase of meiosis 1
Twin spots
are adjacent islands of tissue that differ from both each other and from the tissue surrounding themthis arise from homozygous cells with recessive phenotype growing amid a generally heterozygous cell population displaying a hetrozygous cell population displaying the dominant phenotype
Mosiac
an organism containing tissues of different genotypes
Non disjunction
failures in chromosomes segregation during meosis responsible for defects like trisomy
mitotic chromosome loss
a mechanism causing aneuploidy in which a particular chromatid or chromosome fails to become incorporated in either daughter cell during cell division
Mitotic recombination
is any mitotic process that generates a diploid daughter cell with a combination of alleles different from that of the diploid parental cell
DNA
(deoxyribonucleic acid) is the molecule of heridity that encodes genetic information contains a sugar known as deoxyribose it is found mainly in cell nuclei and is acidic
Nucleotides
a subunit of DNA or RNA consisting of a nitrogenous base (adenine, guanine, thymine, or cytosine in DNA or Adenine, guanine, uracil or cytosine in RNA a phosphate group and a sugar deoxyribose in DNA ribose in RNA
Phosphodiester bonds
covalent bonds joinging one nucleotide to another these bonds are the backbone of DNA
Polymer
a linked chain of repeating subunits that form a larger molecule DNA is a type of polymer
Transformation
is the bacterial mechanism for the transfer of genetic material in which free DNA of one genotype is taken in through the cell surface of bacteria of another genotype and is incorporated into the recipient cell chromosome. In eukaryotic cells, the term transformation refers to the conversion of normal eukaryotic cells into a cancer-like state
Phage
short for bacteriophage a virus for which the natural host is a bacterial cell literally means bacteria eater
Template
a strand of dna or rna that is used as a model by dna or rna polymerase or by reverse transcriptase for the creation of a new complementary base strand of Dna or Rna
Complementary base pairing
during DNA replication base pairing in which a complementary strand aligns opposite the exposed bases on the parent strand to create the nucleotide sequence of the new strand of DNA
Semi conservative replication
a pattern of double helix duplication in which complementary base pairing followed by the linkage of successive nucleotides yields two daughter double helices that each contain one of the original dna strands intact conserved and one completely new strand
initiation
during which proteins open up the double helix and prepare it for complementary base pairing
Elongation
during which proteins connect the correct sequence of nucleotides on both newly formed DNA double helixes
Supercoiling
additional twisting of the DNA molecule caused by movement of the replication fork during unwinding
Dna Topoisomerases
a group of enzymes that help relax supercoiling of the DNA helix by nicking one of both strands to allow the strands to rotate relative to eadh other
Telemeres
specialized terminal structures on eukaryotic chromosomes that ensure the maintenance and accurate replication of the two ends of each linear chromosome
Heteroduplex region
a region of double stranded dna in which two strands have nonidentical though similar sequences heteroduplex regions are often formed as intermediates during crossing over
Gene conversion
any deviation from the expected 2:2 segregation of parental alleles