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49 Cards in this Set

  • Front
  • Back

substantia nigra

- associated with parkinson's


- part of basal ganglia


- supplies DA (dopamine)

basal ganglia

- network of structures that form a ring around the thalamus


- modifies movements by surpressing competing movements; adds "grace" to movements


- controls movement/body position


- sense of direction/distance


-reward/addiction


parts of basal ganglia

putamen, caudate nucleus, globus pallidus, nucleus acumbens, substantia nigra



striatum = putamen & caudate nucleus


limbic system

- network of structures that form a ring around brainstem


- controls emotion, memory, and learning processes, and smell

thalamus

- "relay" station between brainstem


- controls emotions, memory, and learning process, and senses (not smell)

hypothalamus

- pituitary gland


- below thalamus


- regulates behavior


- metabolic functions (autonomic system)


hippocampus

long term memory


cingulate gyrus

emotions/anxiety

amygdala

aggression/fear

pituitary gland

regulates blood pressure, water balance in body, sex organs



- produces hormones

pineal gland

produces melotonin (for sleep)

septal nuclei

reward/reinforcement

fornix

tract of white matter connecting hypothalamus to hippocampus

emotions vs. feelings

emotions: bodily reaction (blood pressure, dilated pupils) provoked by emotionally competent stimuli



feelings: occurs AFTER we become aware in our brain of such physical changes

blood supply to brain

arteries: carries oxygenated blood to body


veins: returns deoxygenated blood back to heart


capillaries: smaller veins/arteries (smallest blood vessels)

cerebral arteries

anterior cerebral artery, middle cerebral artery, and posterior cerebral artery

anterior cerebral artery

- interior frontal lobe, medial frontal, and parietal lobes


- limbic system


- important for thinking, reasoning, planning



problems:


- reduced thinking/reasoning


- impaired planning


- paralysis in legs


middle cerebral artery

- most of cortex


- including basal ganglia


- damage to left MCA = aphasia


- sensory function, spatial, visual, and voluntary movements, speech

posterior cerebral artery

inferior temporal and occipital lobes


- thalamus and limbic system


- visual and coordination


problems: cortical blindness and coordination loss

circle of willis

- protection/back up system


- "circle"


- anterior and posterior communicating arteries provide back up if one gets blocked


- can re-route blood supply

basilar blood system

- fusion of vetebral arteries (where the 2 artieries join together @ base of skull)


- beneath circle of willis


- supplies blood to cerebellum, brain stem, and diff parts of brain

carotid blood system

external carotid: facial muscles, forehead, oral, and nasal cavities



internal carotid: feeds the brain, especially anterior portion

cebrovascular accident (CVA)

- "stroke"


- thrombotic: blood clot (thrombus) blocks flow of blood in brain


- embolic: blood clot breaks away and flows to brain where it blocks an artery


- cerebral hemorrhage: break in blood vessel (aneurysm) in brain

somatosensation

- bodily experienced sensations


- pain, temperature, touch, proprioception


- specialized receptors in skin/muscles


- signal conversion into neural impulses


- projections to spinal cord by dorsal root ganglia


- info sent to primary sensory cortex


- info integration in association cortex

3 neuron organization

1) first order neurons:


- cell bodies in DRG


- collect sensory info from periphery


- transmit to 2nd order


2) second order neurons:


- in spinal cord/brain stem


- projections cross to opposite thalamus


3) third order neurons


- in thalamus


- projections to primary sensory cortex

spinal cord

- spinal cord -> CNS


- spinal nerves -> PNS (31 pairs)


- carries out motor command


- initiates reflex movement


- "lowest level" of motor function

grey matter vs. white matter

grey matter: ends at thoracic/lumbar, processes info


- cell bodies, has no myelin



white matter: continues into lumbar/sacral, transmit info between brain and body


- most decussate


- fibers


- myelinated

afferent nerve fibers (spinal cord)

- sensory/receptor neurons


- ascending


- carry nerve impulses from receptors/sense organs TOWARD CNS


- dorsal root ganglia: sends info from body into cord and up white matter tracts


- dorsal columns, anterolateral, spinothalamic, spinocerebellar


efferent nerve fibers (spinal cord)

- motor neurons


- descending


- carry nerve impulses AWAY from CNS to muscles and glands


- ventral root


- pyramidal and extrapyramidal tracts (coritcospinal, rubrospinal, vestibulospinal)


corticospinal tract

- motor strip -> midbrain -> pons -> medulla -> spinal cord (decussate at medulla)


- efferent


- descending


- part of pyramidal tract


- motor impulses from motor cortex to brain stem


- transmit voluntary motor commands

4 sections of spinal cord

from top to bottom: cervical, thoracic, lumbar, sacral

anterolateral tract

- ascending


- carries a lot of info about emotional processing (sensory receptors: mechano, thermo, noci)


- sensation -> DRG -> dorsal horn -> ant lateral tract -> pons -> thalamus -> sensory strip


- decussate at spinal cord


- to cortex from skin/muscle receptors


- two tracts associated with this:


1) lateral spinothalamic tract: pain and temperature


2) anterior spinothalamic tract: general touch/diffuse touch/un-localized touch/itch


cerebellum role in motor system

- participates in motor planning


- regulates/coordinates ongoing movement


- motor learning/memory (excitatory)


basal ganglia role in motor system

- regulates motor activity and modifies it


- inhibitory


- pieces coming together = system of integration


- network of connections to muscles


- also important for other functions (emotion, personality, cognition)


motor cortex strip in motor system

- highest motor function


- executes movement w/feedback to cortical/subcortical areas


- participates in cognitive planning of motor activity (homunculus)

mechanorecption

touch, pressure, vibration, proprioception (sense of own body)

thermoreception

temperature (cold/heat)

nociception

pain

parkison's disorder

- resting tremor: degenerative changes in substantia nigra


- basal ganglia dysfunction


- low levels of dopamine


- medication for parkinsons = increase dopamine levels

hierarchy of neuronal motor network

highest to lowest: motor cortex, basal ganglia, cerebellum, spinal cord

dorsal horn

sensory cells

ventral horn

motor cells

mamillary bodies

- involved in processing spatial memory and recognition


- adjacent to hypothalamus

where does spinothalamic decussate

does not decussate, goes directly from spine to thalamus

where does corticospinal tract decussate

at medulla (brain stem)

different kinds of sensation

- background: how do you feel? a state a being. (energy)


- primary: easy to identify (fear, anger, happiness)


- social: complex (embarrassment, admiration, envy)

motor loop

- motor impulses and sensory information get sent to putamen


- signal reaches thalamus (both facilitated and inhibited)


- refined projections get sent back to motor cortex as coordinated output

association/cognitive loop


-training loop


- afferents from cortical areas go to caudate nucleus and nucleus acumbens (basil ganglia)


- projections (faciliated and inhibited) reach thalamus


- projections go back to coritcal areas

limbic loop

- emotion/expression loop


- hippocampus, amygdala, limbic lobe project to caudate nucleus & nucleus acumbens


- projections go to thalamus


- then back to limbic lobe